Potential for using simulated altitude as a means of prehabilitation: a physiology study.

altitude training haematological fitness hypoxic conditioning peri-operative medicine prehabilitation

Journal

Anaesthesia
ISSN: 1365-2044
Titre abrégé: Anaesthesia
Pays: England
ID NLM: 0370524

Informations de publication

Date de publication:
12 2023
Historique:
accepted: 03 10 2023
medline: 8 11 2023
pubmed: 25 10 2023
entrez: 25 10 2023
Statut: ppublish

Résumé

The current pandemic of surgical complications necessitates urgent and pragmatic innovation to reduce postoperative morbidity and mortality, which are associated with poor pre-operative fitness and anaemia. Exercise prehabilitation is a compelling strategy, but it has proven difficult to establish that it improves outcomes either in isolation or as part of a multimodal approach. Simulated altitude exposure improves performance in athletes and offers a novel potential means of improving cardiorespiratory and metabolic fitness and alleviating anaemia within the prehabilitation window. We aimed to provide an initial physiological foundation for 'altitude prehabilitation' by determining the physiological effects of one week of simulated altitude (F

Identifiants

pubmed: 37877784
doi: 10.1111/anae.16158
doi:

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1472-1480

Subventions

Organisme : Academy of Medical Sciences
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
Pays : United Kingdom
Organisme : British Heart Foundation
Pays : United Kingdom
Organisme : Versus Arthritis
Pays : United Kingdom
Organisme : Diabetes UK
Pays : United Kingdom

Informations de copyright

© 2023 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists.

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Auteurs

L A Brown (LA)

Royal Melbourne Hospital, Melbourne, Australia.

J A Griffiths (JA)

Nuffield Department of Anaesthesia, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

P Santer (P)

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

P M Jakeman (PM)

Health Research Institute and Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland.

T G Smith (TG)

Centre for Human and Applied Physiological Sciences, King's College London, London, UK.
Department of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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