[Inability of hospital computerised physician order entry systems to secure the use of concentrated potassium intravenous solutions].

Incapacité des logiciels d’aide à la prescription hospitaliers à sécuriser l’utilisation des solutions concentrées de potassium injectable.
Intravenous route Medication error Potassium chloride computerised physician order entry system

Journal

Annales pharmaceutiques francaises
ISSN: 0003-4509
Titre abrégé: Ann Pharm Fr
Pays: France
ID NLM: 2985176R

Informations de publication

Date de publication:
23 Oct 2023
Historique:
received: 04 06 2022
revised: 29 05 2023
accepted: 12 06 2023
medline: 26 10 2023
pubmed: 26 10 2023
entrez: 25 10 2023
Statut: aheadofprint

Résumé

To determine whether hospital computerised physician order entry (CPOE) systems contribute to securing intravenous potassium chloride (KCl) prescriptions with reference to the recommendations issued by French healthcare agencies. We sent a questionnaire to the members of the Association pour le Digital et l'Information en Pharmacie. More than three quarters of the 84 responses received involving 23 CPOE systems indicate that it is possible to : prescribe an ampoule of concentrated potassium chloride 10% 10 mL intravenously without any diluent (80 %); prescribe 4 grams of KCl in a bag of 500 mL of NaCl 0,9% (98 %); prescribe a solution that contains 6 grams of KCl per liter (94 %); prescribe the administration of an injectable ampoule orally by means of a free text comment (83 %). Nearly half of the responses indicate that it is possible to prescribe: concentrated KCl ampouSles as administration solvent (50 %); an injectable vial to be administered by oral route (52 %). At least 23 hospital CPOE systems are unable to secure the prescriptions of injectable KCl. This finding lifts the veil on an unthought, namely the role of CPOE systems in securing high-risk medications. In order to solve this problem, it should be mandatory that health information technology vendors pay particular attention to these drugs. With regard to injectable KCl, the utilisation of a dilution vehicule, maximum concentration and maximum infusion flow rate are the first four constraints to be satisfied.

Identifiants

pubmed: 37879563
pii: S0003-4509(23)00134-7
doi: 10.1016/j.pharma.2023.06.007
pii:
doi:

Types de publication

English Abstract Journal Article

Langues

fre

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2023. Published by Elsevier Masson SAS.

Auteurs

Pauline Klein (P)

Service pharmaceutique, Hôpital de la Croix-Rousse, groupement hospitalier Nord, hospices civils de Lyon, 103 grande rue de la Croix Rousse, 69317 Lyon Cedex 04, France. Electronic address: pauline.klein@orange.fr.

Jeremy Bonhomme (J)

OMEDIT Océan Indien - ARS La Réunion 2bis, Avenue Georges Brassens CS 61002 - 97743 Saint Denis CEDEX 9 - La Réunion, France.

Cindy Bourne (C)

Service pharmaceutique, Centre hospitalier de Crest, rue Paul GOY, 26400 CREST, France.

Magali Hellot-Guersing (M)

Service pharmaceutique, Centre Hospitalier Lucien Hussel, Montée du Dr Chapuis, 38200 Vienne, France.

Charles Marcucci (C)

Service pharmaceutique, Centre Hospitalier de Clermont de l'Oise, Rue Frédéric Raboisson, BP 40024, 60607 Clermont Cedex, France.

Simon Rodier (S)

Service pharmaceutique, Centre Hospitalier Intercommunal Alençon Mamers, 25 Rue de Fresnay, 61000 Alençon, France.

Bruno Charpiat (B)

Service pharmaceutique, Hôpital de la Croix-Rousse, groupement hospitalier Nord, hospices civils de Lyon, 103 grande rue de la Croix Rousse, 69317 Lyon Cedex 04, France.

Classifications MeSH