Drug-induced liver injury with autoimmune features secondary to infliximab for ulcerative colitis.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
24 Oct 2023
Historique:
pmc-release: 24 10 2025
medline: 27 10 2023
pubmed: 26 10 2023
entrez: 25 10 2023
Statut: epublish

Résumé

We present a patient with a drug-induced liver injury with autoimmune features as a result of infliximab therapy for ulcerative colitis. This is a rare but serious side effect in patients receiving this treatment which clinicians should consider in the event of liver function test derangement.

Identifiants

pubmed: 37879703
pii: 16/10/e254272
doi: 10.1136/bcr-2022-254272
pmc: PMC10603518
pii:
doi:

Substances chimiques

Infliximab B72HH48FLU
Gastrointestinal Agents 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: JPS has received speaker fees from AbbVie, Fresenius Kabi, Galapagos, Janssen-Cilag, Pharmacosmos, Takeda and Tillotts Pharma. He has received advisory board fees from AbbVie, Bristol Myers Squibb, Dr Falk Pharma and Galapagos.

Auteurs

Ailsa Gemmell (A)

Queen Elizabeth University Hospital, NHSGGC, Glasgow, UK ailsa.gemmell@nhs.scot.

Andrew Fraser (A)

Gastroenterology, Queen Elizabeth University Hospital, Glasgow, UK.

Karin Oien (K)

Pathology, Queen Elizabeth University Hospital, Glasgow, UK.

John Paul Seenan (JP)

Gastroenterology, Queen Elizabeth University Hospital, Glasgow, UK.

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Classifications MeSH