Genome editing with retroelements.

CRISPR-Cas Systems Gene Editing / methods Retroelements RNA, Guide, CRISPR-Cas Systems / chemistry Mutagenesis, Insertional / methods CRISPR-Associated Protein 9 / chemistry Genome, Human Humans

Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
27 10 2023
Historique:
medline: 30 10 2023
pubmed: 26 10 2023
entrez: 26 10 2023
Statut: ppublish

Résumé

RNA-guided DNA writing enzymes offer promise for programmable gene insertion.

Identifiants

DOI: 10.1126/science.adi3183 PMID: 37883564
pubmed: 37883564
doi: 10.1126/science.adi3183
doi:

Substances chimiques

Retroelements 0
RNA, Guide, CRISPR-Cas Systems 0
CRISPR-Associated Protein 9 EC 3.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

370-371

Auteurs

Stephen Tang (S)

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Samuel H Sternberg (SH)

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Systèmes CRISPR-Cas › Genome editing with retroelements.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Édition de gène › Genome editing with retroelements.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Séquences répétées dispersées › Rétroéléments › Genome editing with retroelements.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › Systèmes CRISPR-Cas, ARN, guide › Genome editing with retroelements.
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Mutagenèse par insertion › Genome editing with retroelements.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines associées aux CRISPR › Protéine-9 associée à CRISPR › Genome editing with retroelements.
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome humain › Genome editing with retroelements.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genome editing with retroelements.