An unusual presentation of a primary lung adenocarcinoma: A case report.

Case report Gastrointestinal metastasis Lung cancer Metastasis Surgical resection Tumour markers

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 16 08 2023
revised: 19 10 2023
accepted: 21 10 2023
medline: 27 10 2023
pubmed: 27 10 2023
entrez: 26 10 2023
Statut: ppublish

Résumé

Lung cancer is one of the most common malignancies worldwide and common sites of metastasis are to brain, liver, adrenal glands, and bones [1]. Metastasis to the gastrointestinal (GI) tract is extremely rare (<1%) and the most common site is the small intestine [5]. A 60-year-old female referred for intermittent colicky abdominal pain and diarrhoea, with cross-sectional imaging showing a distal small bowel mass with lymphadenopathy. Malignancy workup revealed an additional mediastinal mass and raised tumour marker carcinoembryonic antigen (CEA). Bronchoscopy confirmed primary lung adenocarcinoma of the mediastinal mass. Given the raised CEA, evolving obstructive symptoms, and concerns for synchronous lung and gastrointestinal primaries, the patient proceeded to have a small bowel resection leading to the diagnosis of a GI lung metastasis. If Symptomatic, suggested treatment of lung metastasis to the GI tract is surgical resection. Current evidence suggests that in isolated GI metastases, resection may have a therapeutic benefit and an association with overall survival rate. In patients with symptomatic or isolated GI lung metastasis, surgical resection should be considered for treatment and management of metastatic disease. The role of tumour marker CEA in primary lung adenocarcinoma is unclear.

Identifiants

pubmed: 37883873
pii: S2210-2612(23)01096-9
doi: 10.1016/j.ijscr.2023.108967
pmc: PMC10667878
pii:
doi:

Types de publication

Case Reports

Langues

eng

Pagination

108967

Informations de copyright

Crown Copyright © 2023. Published by Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest statement N/A.

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Auteurs

Callie Killoran (C)

Department of Surgery, Sunshine Coast University Hospital, 6 Doherty Street, Birtinya, Queensland 4575, Australia. Electronic address: callie.killoran@my.jcu.edu.au.

Renee A Tabone (RA)

Department of Surgery, Sunshine Coast University Hospital, 6 Doherty Street, Birtinya, Queensland 4575, Australia; Griffith University, School of Medicine and Dentistry, Parklands Drive, Southport, Gold Coast Campus Griffith University, Queensland 4222, Australia. Electronic address: renee.tabone@health.qld.gov.au.

Emily Olive (E)

Department of Surgery, Sunshine Coast University Hospital, 6 Doherty Street, Birtinya, Queensland 4575, Australia. Electronic address: emily.olive@health.qld.gov.au.

Nicholas Bell-Allen (N)

Department of Surgery, Sunshine Coast University Hospital, 6 Doherty Street, Birtinya, Queensland 4575, Australia. Electronic address: nicholas.bell-allen@health.qld.gov.au.

Katherine Wilson (K)

Department of Surgery, Sunshine Coast University Hospital, 6 Doherty Street, Birtinya, Queensland 4575, Australia; Griffith University, School of Medicine and Dentistry, Parklands Drive, Southport, Gold Coast Campus Griffith University, Queensland 4222, Australia. Electronic address: katherine.wilson@health.qld.gov.au.

Classifications MeSH