Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding.

gallbladder polyps laparoscopic cholecystectomy papillary-tubular neoplasm pathological study.

Journal

Recent patents on anti-cancer drug discovery
ISSN: 2212-3970
Titre abrégé: Recent Pat Anticancer Drug Discov
Pays: United Arab Emirates
ID NLM: 101266081

Informations de publication

Date de publication:
25 Oct 2023
Historique:
received: 05 05 2023
revised: 29 08 2023
accepted: 08 09 2023
medline: 27 10 2023
pubmed: 27 10 2023
entrez: 27 10 2023
Statut: aheadofprint

Résumé

Intracholecystic papillary neoplasms (ICPNs) represent a rare benign entity characterized by intraluminal polypoid lesions in the gallbladder. The incidence of ICPNs ranges from 0.4% to 0.61% in all gallbladder specimens. In this report, we present a case of a young Caucasian woman who underwent elective laparoscopic cholecystectomy due to gallbladder polyps. The histological examination revealed the presence of an intracholecystic papillary neoplasm (ICPN) with a tubulopapillary growth pattern, exhibiting gastric morphology and displaying both low and high-grade dysplasia. A thorough review of the existing literature was conducted, with a specific focus on the histological features. A comprehensive understanding of neoplastic polyps of the gallbladder is still limited. Pathological examination of these lesions is crucial for identifying key features that can influence patient outcomes and survival.

Sections du résumé

BACKGROUND BACKGROUND
Intracholecystic papillary neoplasms (ICPNs) represent a rare benign entity characterized by intraluminal polypoid lesions in the gallbladder. The incidence of ICPNs ranges from 0.4% to 0.61% in all gallbladder specimens.
CASE PRESENTATION METHODS
In this report, we present a case of a young Caucasian woman who underwent elective laparoscopic cholecystectomy due to gallbladder polyps. The histological examination revealed the presence of an intracholecystic papillary neoplasm (ICPN) with a tubulopapillary growth pattern, exhibiting gastric morphology and displaying both low and high-grade dysplasia. A thorough review of the existing literature was conducted, with a specific focus on the histological features.
CONCLUSION CONCLUSIONS
A comprehensive understanding of neoplastic polyps of the gallbladder is still limited. Pathological examination of these lesions is crucial for identifying key features that can influence patient outcomes and survival.

Identifiants

pubmed: 37885107
pii: PRA-EPUB-135601
doi: 10.2174/0115748928256837231012151452
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Antonio Pesce (A)

Section of General Surgery, University of Ferrara, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy.

Valentina Sani (V)

Section of General Surgery, University of Ferrara, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy.

Alba Gaban (A)

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara and S. Anna University Hospital, Ferrara, Italy.

Nicolò Fabbri (N)

Section of General Surgery, University of Ferrara, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy.

Massimo Tilli (M)

Department of Radiology, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy.

Roberta Gafà (R)

Department of Morphology, Surgery and Experimental Medicine, University of Ferrara and S. Anna University Hospital, Ferrara, Italy.

Carlo Vittorio Feo (CV)

Section of General Surgery, University of Ferrara, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy.

Classifications MeSH