Guideline adherence in the use of coronary angiography in patients presenting at the emergency department without myocardial infarction - Results from the German ENLIGHT-KHK project.

Chest pain Coronary angiography Emergency department Guideline Guideline adherence

Journal

International journal of cardiology. Heart & vasculature
ISSN: 2352-9067
Titre abrégé: Int J Cardiol Heart Vasc
Pays: Ireland
ID NLM: 101649525

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 03 09 2023
revised: 29 09 2023
accepted: 11 10 2023
medline: 27 10 2023
pubmed: 27 10 2023
entrez: 27 10 2023
Statut: epublish

Résumé

For patients with acute myocardial infarction (AMI), direct coronary angiography (CA) is recommended, while for non-AMI patients, the diagnostic work-up depends on clinical criteria. This analysis provides initial prospective German data for the degree of guideline-adherence (GL) in the use of CA on non-AMI patients presenting at the emergency department (ED) with suspected acute coronary syndrome (ACS) according to the 2015 ESC-ACS-GL. Furthermore the implications of the application of the 2020 ESC-ACS-GL recommendations were evaluated. Patient symptoms were identified using a standardized questionnaire; medical history and diagnostic work-up were acquired from health records. In accordance with the 2015 ESC-ACS-GL, CA was considered GL-adherent if intermediate risk criteria (IRC) were present or non-invasive, image-guided testing (NIGT) was pathological. Between January 2019 and August 2021, 229 patients were recruited across seven centers. Patients presented with chest pain, dyspnea, and other symptoms in 66.7%, 16.2% and 17.1%, respectively, were in mean 66.3 ± 10.5 years old, and 36.3% were female. In accordance with the 2015 ESC-ACS-GL, the use of CA was GL-adherent for 64.0% of the patients. GL-adherent compared to non-adherent use of CA resulted in revascularization more often (44.5% vs. 17.1%, p < 0.001). Applying the 2020 ESC-ACS-GL, 20.4% of CA would remain GL-adherent. In the majority of cases, the use of CA was adherent to the 2015 ESC-ACS-GL. With regard to the 2020 and 2023 ESC-ACS-GL, efforts to expand the utilization of NIGT are crucial, especially as GL-adherent use of CA is more likely to result in revascularization.(German Clinical Trials Register DRKS00015638; https://drks.de/search/de/trial/DRKS00015638; (registration date: 19 February 2019)).

Sections du résumé

Background UNASSIGNED
For patients with acute myocardial infarction (AMI), direct coronary angiography (CA) is recommended, while for non-AMI patients, the diagnostic work-up depends on clinical criteria. This analysis provides initial prospective German data for the degree of guideline-adherence (GL) in the use of CA on non-AMI patients presenting at the emergency department (ED) with suspected acute coronary syndrome (ACS) according to the 2015 ESC-ACS-GL. Furthermore the implications of the application of the 2020 ESC-ACS-GL recommendations were evaluated.
Methods UNASSIGNED
Patient symptoms were identified using a standardized questionnaire; medical history and diagnostic work-up were acquired from health records. In accordance with the 2015 ESC-ACS-GL, CA was considered GL-adherent if intermediate risk criteria (IRC) were present or non-invasive, image-guided testing (NIGT) was pathological.
Results UNASSIGNED
Between January 2019 and August 2021, 229 patients were recruited across seven centers. Patients presented with chest pain, dyspnea, and other symptoms in 66.7%, 16.2% and 17.1%, respectively, were in mean 66.3 ± 10.5 years old, and 36.3% were female. In accordance with the 2015 ESC-ACS-GL, the use of CA was GL-adherent for 64.0% of the patients. GL-adherent compared to non-adherent use of CA resulted in revascularization more often (44.5% vs. 17.1%, p < 0.001). Applying the 2020 ESC-ACS-GL, 20.4% of CA would remain GL-adherent.
Conclusions UNASSIGNED
In the majority of cases, the use of CA was adherent to the 2015 ESC-ACS-GL. With regard to the 2020 and 2023 ESC-ACS-GL, efforts to expand the utilization of NIGT are crucial, especially as GL-adherent use of CA is more likely to result in revascularization.(German Clinical Trials Register DRKS00015638; https://drks.de/search/de/trial/DRKS00015638; (registration date: 19 February 2019)).

Identifiants

pubmed: 37886218
doi: 10.1016/j.ijcha.2023.101281
pii: S2352-9067(23)00112-4
pmc: PMC10597756
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101281

Informations de copyright

© 2023 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Bastian Wein (B)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.
Cardiology, Faculty of Medicine, University of Augsburg, Germany.

Yana Seleznova (Y)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Dirk Mueller (D)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Marie Naumann (M)

Institute for Health Economics and Clinical Epidemiology, University of Cologne, Germany.

Simon Loeser (S)

AOK Rheinland-Hamburg, Dusseldorf, Germany.

Melanie Steffen (M)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.

Ute Windhoevel (U)

CERC Deutschland GmbH, Essen, Germany.

Michael Haude (M)

Rheinlandklinikum Neuss, Germany.

Juergen Vom Dahl (J)

Mariahilf Hospital, Moenchengladbach, Germany.

Ulrich Schaefer (U)

Heart and Vascular Centre, Bad Bevensen, Germany.

Moritz Montenbruck (M)

Marien-Hospital, Hamburg, Germany.

Ruediger Jegodka (R)

Elisabeth Hospital, Recklinghausen, Germany.

Thorsten Dill (T)

Sana Hospital Benrath, Medical Department, Dusseldorf, Germany.

Jan-Erik Guelker (JE)

Petrus Hospital, Department of Cardiology and Rhythmology, Wuppertal, Germany.
University Witten/Herdecke, Faculty of Health, Witten, Germany.

Dirk Boese (D)

Hochsauerland Hospital, Department of Cardiology, Arnsberg, Germany.

Björn Bogs (B)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.

Eva Harmel (E)

Cardiology, Faculty of Medicine, University of Augsburg, Germany.

Oliver Bruder (O)

Elisabeth-Hospital, Contilia Heart and Vascular Centre, Essen, Germany.
Ruhr University Bochum, Germany.

Classifications MeSH