A Scan of Pleiotropic Immune Mediated Disease Genes Identifies Novel Determinants of Baseline FVIII Inhibitor Status in Hemophilia-A.
Autoimmune-/autoinflammatory-disorders
Candidate gene
Factor VIII
Factor VIII gene (F8) mutations
Factor VIII inhibitors
Gene-centric association scan
Hemophilia A
Immune-mediated disease genes and gene variants
Immune-mediated diseases
Pleiotropic
Race/ethnicity
Journal
Research square
Titre abrégé: Res Sq
Pays: United States
ID NLM: 101768035
Informations de publication
Date de publication:
18 Oct 2023
18 Oct 2023
Historique:
pubmed:
27
10
2023
medline:
27
10
2023
entrez:
27
10
2023
Statut:
epublish
Résumé
Hemophilia-A (HA) is caused by heterogeneous loss-of-function factor (F)VIII gene (
Identifiants
pubmed: 37886476
doi: 10.21203/rs.3.rs-3371095/v1
pmc: PMC10602130
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : NCRR NIH HHS
ID : C06 RR020547
Pays : United States
Organisme : NHLBI NIH HHS
ID : K08 HL071130
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL072533
Pays : United States
Organisme : NHLBI NIH HHS
ID : RC2 HL101851
Pays : United States
Déclaration de conflit d'intérêts
CONFLICTS OF INTEREST There are NO relevant conflicts for any co-author. H. Mead is an employee of BioMarin.
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