Employing of Curcumin-Silver Nanoparticle-Incorporated Sodium Alginate-Co-Acacia Gum Film Hydrogels for Wound Dressing.

Arabic gum hydrogel chronic wounds curcumin silver silver nanoparticles

Journal

Gels (Basel, Switzerland)
ISSN: 2310-2861
Titre abrégé: Gels
Pays: Switzerland
ID NLM: 101696925

Informations de publication

Date de publication:
25 Sep 2023
Historique:
received: 30 08 2023
revised: 18 09 2023
accepted: 21 09 2023
medline: 27 10 2023
pubmed: 27 10 2023
entrez: 27 10 2023
Statut: epublish

Résumé

Skin wound healing is time-consuming and frequently accompanied by bacterial infections and the development of scars. The rise of antibiotic-resistant bacterial strains has sparked a growing interest in naturally occurring bioactive substances, like curcumin, that possess wound-healing capabilities. Silver is a natural antimicrobial agent, and finds extensive use in specialized wound dressings. Silver nanoparticles (AgNPs) were synthesized using an eco-friendly approach, employing curcumin. The prepared nanoparticles have been characterized using TEM, DLS, and zeta potential. The prepared AgNPs were loaded on sodium alginate-co-gum arabic hydrogel. Two hydrogel samples (with and without AgNPs) have been applied for wound healing. The developed silver nanoparticles that were created exhibited effective action against both types of bacteria, namely

Identifiants

pubmed: 37888353
pii: gels9100780
doi: 10.3390/gels9100780
pmc: PMC10606815
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : King Saud University
ID : RSP2023R506

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Auteurs

Fahad M Aldakheel (FM)

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11433, Saudi Arabia.

Dalia Mohsen (D)

Clinical Laboratory Sciences Program, Inaya Medical College, Riyadh 12211, Saudi Arabia.
Microbiology Department, National Research Centre, Giza 12622, Egypt.

Marwa M El Sayed (MM)

Chemical Engineering and Pilot Plant Department, National Research Centre, Giza 12622, Egypt.

Mohammed H Fagir (MH)

Clinical Laboratory Sciences Program, Inaya Medical College, Riyadh 12211, Saudi Arabia.

Dalia K El Dein (DK)

Clinical Laboratory Sciences Program, Inaya Medical College, Riyadh 12211, Saudi Arabia.

Classifications MeSH