The Antiviral Potential of Algal Lectins.

bioactive compounds lectins macroalgae marine biotechnology mechanisms of action microalga seaweed virus

Journal

Marine drugs
ISSN: 1660-3397
Titre abrégé: Mar Drugs
Pays: Switzerland
ID NLM: 101213729

Informations de publication

Date de publication:
28 Sep 2023
Historique:
received: 18 07 2023
revised: 22 09 2023
accepted: 26 09 2023
medline: 30 10 2023
pubmed: 27 10 2023
entrez: 27 10 2023
Statut: epublish

Résumé

Algae have emerged as fascinating subjects of study due to their vast potential as sources of valuable metabolites with diverse biotechnological applications, including their use as fertilizers, feed, food, and even pharmaceutical precursors. Among the numerous compounds found in algae, lectins have garnered special attention for their unique structures and carbohydrate specificities, distinguishing them from lectins derived from other sources. Here, a comprehensive overview of the latest scientific and technological advancements in the realm of algal lectins with a particular focus on their antiviral properties is provided. These lectins have displayed remarkable effectiveness against a wide range of viruses, thereby holding great promise for various antiviral applications. It is worth noting that several alga species have already been successfully commercialized for their antiviral potential. However, the discovery of a diverse array of lectins with potent antiviral capabilities suggests that the field holds immense untapped potential for further expansion. In conclusion, algae stand as a valuable and versatile resource, and their lectins offer an exciting avenue for developing novel antiviral agents, which may lead to the development of cutting-edge antiviral therapies.

Identifiants

pubmed: 37888450
pii: md21100515
doi: 10.3390/md21100515
pmc: PMC10608189
pii:
doi:

Substances chimiques

Lectins 0
Antiviral Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fundação para a Ciência e Tecnologia
ID : UID/MAR/04292/2020
Organisme : Fundação para a Ciência e Tecnologia
ID : LA/P/0069/2020
Organisme : Fundação para a Ciência e Tecnologia
ID : 2021.03113.CEECIND
Organisme : FEDER - Fundo Europeu de Desenvolvimento Regional da União Europeia
ID : SAICTCOVID/72543/2020

Références

Antimicrob Agents Chemother. 1997 Jul;41(7):1521-30
pubmed: 9210678
Nat Struct Biol. 1998 Jul;5(7):571-8
pubmed: 9665171
Viruses. 2021 Mar 25;13(4):
pubmed: 33806073
Antimicrob Agents Chemother. 2011 Jan;55(1):264-75
pubmed: 20956603
Antimicrob Agents Chemother. 2001 Mar;45(3):664-72
pubmed: 11181340
Crit Rev Microbiol. 2015 Feb;41(1):77-88
pubmed: 23855360
J Mol Biol. 2007 Jun 1;369(2):451-61
pubmed: 17434526
Biomed Pharmacother. 2022 Feb;146:112507
pubmed: 34891122
J Virol. 1999 May;73(5):4360-71
pubmed: 10196334
Appl Microbiol Biotechnol. 2011 Jan;89(1):45-55
pubmed: 20890754
Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6029-30
pubmed: 19357305
Retrovirology. 2015 Jan 23;12:6
pubmed: 25613831
Chem Soc Rev. 2021 Mar 21;50(6):3647-3655
pubmed: 33524090
Front Plant Sci. 2020 Sep 10;11:559986
pubmed: 33013979
Comp Biochem Physiol B Biochem Mol Biol. 2000 Feb;125(2):169-77
pubmed: 10817903
Mar Drugs. 2012 Dec 12;10(12):2795-816
pubmed: 23235364
Antiviral Res. 2014 Dec;112:1-7
pubmed: 25265598
Front Plant Sci. 2020 Mar 17;11:279
pubmed: 32256509
Protein Sci. 2007 Dec;16(12):2756-60
pubmed: 17965185
Mar Drugs. 2019 Jul 26;17(8):
pubmed: 31357490
Bioimpacts. 2018;8(2):139-151
pubmed: 29977835
Mar Drugs. 2021 Dec 01;19(12):
pubmed: 34940686
J Biol Chem. 2011 Jun 3;286(22):19446-58
pubmed: 21460211
Mar Drugs. 2017 Aug 16;15(8):
pubmed: 28813016
Antimicrob Agents Chemother. 2003 Aug;47(8):2518-25
pubmed: 12878514
Antivir Chem Chemother. 2007;18(6):317-27
pubmed: 18320936
Food Chem Toxicol. 2019 Dec;134:110827
pubmed: 31542433
J Virol. 2000 May;74(10):4562-9
pubmed: 10775592
Biol Pharm Bull. 2006 Oct;29(10):2135-9
pubmed: 17015966
J Biol Chem. 2016 Sep 2;291(36):18967-76
pubmed: 27402833
Front Microbiol. 2017 May 09;8:755
pubmed: 28536555
Mar Drugs. 2021 Jul 26;19(8):
pubmed: 34436255
Asian J Transfus Sci. 2016 Jan-Jun;10(1):12-21
pubmed: 27011665
Mar Drugs. 2022 Jan 26;20(2):
pubmed: 35200632
Structure. 2011 Aug 10;19(8):1170-81
pubmed: 21827952
Mar Drugs. 2021 Feb 06;19(2):
pubmed: 33562153
Molecules. 2021 Aug 24;26(17):
pubmed: 34500548
Antiviral Res. 2016 Sep;133:1-8
pubmed: 27424494
J Biol Chem. 2011 Jun 10;286(23):20788-96
pubmed: 21471192
Mar Drugs. 2019 Oct 06;17(10):
pubmed: 31590428
Antimicrob Agents Chemother. 2020 May 21;64(6):
pubmed: 32229493
Structure. 2006 Jul;14(7):1127-35
pubmed: 16843894
J Biol Chem. 2002 Sep 13;277(37):34336-42
pubmed: 12110688
J Nat Prod. 1993 Jul;56(7):1123-9
pubmed: 8104236
J Biol Chem. 2006 Sep 1;281(35):25177-83
pubmed: 16809348
Nat Rev Immunol. 2023 Aug;23(8):479-494
pubmed: 36646848
J Biol Chem. 2012 Sep 28;287(40):33796-811
pubmed: 22865886
Methods Mol Biol. 2017;1560:93-107
pubmed: 28155147
Front Microbiol. 2017 Jul 11;8:1199
pubmed: 28744257
Biol Pharm Bull. 2007 Aug;30(8):1573-5
pubmed: 17666824
AIDS. 2004 Nov 5;18(16):2115-25
pubmed: 15577644
J Biol Chem. 2010 Aug 6;285(32):24845-54
pubmed: 20507987
PLoS One. 2015 Aug 07;10(8):e0135340
pubmed: 26252012
Antioxidants (Basel). 2020 May 07;9(5):
pubmed: 32392759
AIDS Res Hum Retroviruses. 2012 Feb;28(2):206-14
pubmed: 21793733
Front Public Health. 2020 Nov 11;8:560389
pubmed: 33262966
ACS Infect Dis. 2016 Nov 11;2(11):882-891
pubmed: 27669574
Arch Virol. 2019 May;164(5):1259-1269
pubmed: 30903291
Cell. 2019 Sep 5;178(6):1526-1541.e16
pubmed: 31474372
Biomolecules. 2020 Feb 19;10(2):
pubmed: 32092955
PLoS One. 2010 Dec 16;5(12):e14360
pubmed: 21179548
Biochem Pharmacol. 2015 Jan 1;93(1):1-10
pubmed: 25481298
Front Immunol. 2019 Oct 09;10:2379
pubmed: 31649680
PLoS One. 2013 May 31;8(5):e64132
pubmed: 23741304
Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211002621
pubmed: 33726557
Antimicrob Agents Chemother. 2013 Aug;57(8):3976-89
pubmed: 23752505
J Appl Phycol. 2018;30(3):1833-1858
pubmed: 32214665
Glycobiology. 2006 Jul;16(7):635-40
pubmed: 16567368
Nat Rev Immunol. 2008 Jun;8(6):447-57
pubmed: 18469831
Viruses. 2020 Feb 11;12(2):
pubmed: 32054060
Medchemcomm. 2019 Jan 14;10(3):390-398
pubmed: 30996857
Med Res Rev. 2016 Mar;36(2):221-47
pubmed: 26290041
Mol Biol Rep. 2022 Dec;49(12):12239-12246
pubmed: 36138301

Auteurs

Christian Alvarez (C)

MARE-Marine and Environmental Sciences Centre & ARNET-Aquatic Research Infrastructure Network Associated Laboratory, ESTM, Polytechnic of Leiria, 2520-641 Peniche, Portugal.

Carina Félix (C)

MARE-Marine and Environmental Sciences Centre & ARNET-Aquatic Research Infrastructure Network Associated Laboratory, ESTM, Polytechnic of Leiria, 2520-641 Peniche, Portugal.

Marco F L Lemos (MFL)

MARE-Marine and Environmental Sciences Centre & ARNET-Aquatic Research Infrastructure Network Associated Laboratory, ESTM, Polytechnic of Leiria, 2520-641 Peniche, Portugal.

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