HumanLectome, an update of UniLectin for the annotation and prediction of human lectins.
Journal
Nucleic acids research
ISSN: 1362-4962
Titre abrégé: Nucleic Acids Res
Pays: England
ID NLM: 0411011
Informations de publication
Date de publication:
27 Oct 2023
27 Oct 2023
Historique:
accepted:
06
10
2023
revised:
03
10
2023
received:
04
09
2023
medline:
27
10
2023
pubmed:
27
10
2023
entrez:
27
10
2023
Statut:
aheadofprint
Résumé
The UniLectin portal (https://unilectin.unige.ch/) was designed in 2019 with the goal of centralising curated and predicted data on carbohydrate-binding proteins known as lectins. UniLectin is also intended as a support for the study of lectomes (full lectin set) of organisms or tissues. The present update describes the inclusion of several new modules and details the latest (https://unilectin.unige.ch/humanLectome/), covering our knowledge of the human lectome and comprising 215 unevenly characterised lectins, particularly in terms of structural information. Each HumanLectome entry is protein-centric and compiles evidence of carbohydrate recognition domain(s), specificity, 3D-structure, tissue-based expression and related genomic data. Other recent improvements regarding interoperability and accessibility are outlined.
Identifiants
pubmed: 37889052
pii: 7331022
doi: 10.1093/nar/gkad905
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Université Grenoble Alpes
Organisme : Glyco@Alps
ID : ANR-15-IDEX-02
Organisme : Labex Arcane
ID : ANR-17-EURE-0003
Organisme : Swiss Federal Government
Organisme : State Secretariat for Education, Research and Innovation
Organisme : Swiss Institute of Bioinformatics and hosted at the Vital-IT Competency Center
Organisme : University of Geneva
Informations de copyright
© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.