Establishment of a novel classification system for alveolar morphology in infants with unilateral complete cleft lip and palate.
Alveolar morphology
Classification system
Mathematical clustering
Presurgical nasoalveolar molding
Unilateral complete cleft lip and palate
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
31
05
2023
accepted:
18
10
2023
pubmed:
27
10
2023
medline:
27
10
2023
entrez:
27
10
2023
Statut:
ppublish
Résumé
Unilateral complete cleft lip and palate (UCCLP) is one of the most severe clinical subtypes among cleft lip and palate (CLP), making repair surgery and subsequent orthodontic treatment particularly challenging. Presurgical nasoalveolar molding (PNAM) has shown conflicting and heterogeneous results in the treatment of UCCLP patients, raising questions about whether the diversity in alveolar anatomical morphology among these patients plays a role in the effectiveness of PNAM treatment. We collected 90 digital maxillary models of infants with UCCLP and performed mathematical clustering analysis, including principal component analysis (PCA), decision tree modeling, and area under the ROC Curve (AUC) analysis, to classify alveolar morphology and identify key measurements. We also conducted clinical evaluations to assess the association between the alveolar morphology and CLP treatment outcomes. Using mathematical clustering analysis, we classified the alveolar morphology into three distinct types: average form, horizontal form, and longitudinal form. The decision tree model, AUC analysis, and comparison analysis revealed that four measurements (Trans AC Overall, our findings establish a novel quantitative classification system for the morphology of alveolar bone in infants with UCCLP and suggest that this classification may be associated with the outcomes of CLP treatment. The multidisciplinary CLP team should thoroughly evaluate and classify the specific alveolar morphology when administering PNAM to infants with UCCLP.
Identifiants
pubmed: 37889344
doi: 10.1007/s00784-023-05353-z
pii: 10.1007/s00784-023-05353-z
pmc: PMC10713668
doi:
Types de publication
Journal Article
Langues
eng
Pagination
7643-7650Subventions
Organisme : National Natural Science Foundation of China
ID : No. 82370909
Organisme : National Natural Science Foundation of China
ID : No. 82001030
Informations de copyright
© 2023. The Author(s).
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