Delayed onset Bickerstaff brainstem encephalitis overlapping Miller-Fisher Syndrome during SARS-CoV-2 infection.


Journal

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
ISSN: 1590-3478
Titre abrégé: Neurol Sci
Pays: Italy
ID NLM: 100959175

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 30 08 2023
accepted: 17 10 2023
medline: 14 11 2023
pubmed: 27 10 2023
entrez: 27 10 2023
Statut: ppublish

Résumé

Bickerstaff brainstem encephalitis (BBE) is a neuroimmunologic disease characterized by the acute onset of external ophthalmoplegia, ataxia, and consciousness disturbance, mostly subsequent to an infection. BBE is considered to be a variant of Miller-Fisher syndrome (MFS), which also exhibits external ophthalmoplegia and ataxia but not presenting consciousness alterations. Therefore, these two medical conditions are included in the clinical spectrum of the "Fisher-Bickerstaff syndrome" ( Shahrizaila and Yuki in J Neurol Neurosurg Psychiatry 84(5):576-583) [1]. With regard to the etiopathogenesis, increasing evidence worldwide suggests that SARS-CoV-2 infection-enhanced immune response is involved in a wide range of neurological complications such as Guillain-Barré syndrome (GBS), MFS, acute necrotizing encephalitis (ANE), myelitis, acute disseminated encephalomyelitis (ADEM), and, although very rarely, BBE either (Hosseini et al. in Rev Neurosci 32:671-691) [2]. We report a case of a patient affected by delayed onset BBE overlapping MFS during a mild SARS-CoV-2 infection. To the best of our knowledge, similar cases have never been reported.

Identifiants

pubmed: 37889381
doi: 10.1007/s10072-023-07142-8
pii: 10.1007/s10072-023-07142-8
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4179-4182

Informations de copyright

© 2023. Fondazione Società Italiana di Neurologia.

Références

Shahrizaila N, Yuki N (2013) Bickerstaff brainstem encephalitis and Fisher syndrome: anti-GQ1b antibody syndrome. J Neurol Neurosurg Psychiatry 84(5):576–583. https://doi.org/10.1136/jnnp-2012-302824
Hosseini N, Nadjafi S, Ashtary B (2021) Overview of COVID-19 and neurological complications. Rev Neurosci 32(6):671–691. https://doi.org/10.1515/revneuro-2020-0116
doi: 10.1515/revneuro-2020-0116 pubmed: 33583157
Krihara T, Igarashi Y, Kobai K, Mizobuchi T, Ishii H, Matsumoto N, Yokobori S, Yokota H (2020) Diagnosis and prediction of prognosis for Bickerstaff’s brainstem encephalitis using auditory brainstem response: a case report. Acute Med Surg. 7(1):e517. https://doi.org/10.1002/ams2.517
doi: 10.1002/ams2.517
Koga M (2013) Bickerstaff brainstem encephalitis: epidemiology, diagnosis, and therapy. Nihon Rinsho 71(5):898–903
pubmed: 23777102
Odaka M, Yuki N, Hirata K (2001) Anti-GQ1b IgG antibody syndrome: clinical and immunological range. J Neurol Neurosurg Psychiatry 70:50–55
Yoshikawa K, Kuwahara M, Morikawa M, Kusunoki S (2020) Bickerstaff brainstem encephalitis with or without anti-GQ1b antibody. Neurol Neuroimmunol Neuroinflamm 7:e889. https://doi.org/10.1212/NXI.0000000000000889
doi: 10.1212/NXI.0000000000000889 pubmed: 32934014 pmcid: 7524576
Guasp M, Muñoz-Sánchez G, Martínez-Hernández E, Santana D, Carbayo Á, Naranjo L, Bolós U, Framil M, Saiz A, Balasa M, Ruiz-García R, Sánchez-Valle R, Barcelona Neuro-COVID Study Group (2022) CSF biomarkers in COVID-19 associated encephalopathy and encephalitis predict long-term outcome. Front Immunol 13:866153. https://doi.org/10.3389/fimmu.2022.866153
doi: 10.3389/fimmu.2022.866153 pubmed: 35479062 pmcid: 9035899
Imai T, Shimizu T, Hagiwara Y, Hirayama T, Hasegawa Y (2013) A case of Bickerstaff brainstem encephalitis successfully treated with intravenous immunoglobulin and methylprednisolone after unsuccessful immunoadsorption plasmapheresis. Open J Clin Diagn 3:1–4. https://doi.org/10.4236/ojcd.2013.31001
doi: 10.4236/ojcd.2013.31001
Llorente Ayuso L, Torres Rubio P, Beijinho do Rosário RF, Giganto Arroyo ML, Sierra-Hidalgo F (2021) Bickerstaff encephalitis after COVID-19. J Neurol 268(6):2035-2037. https://doi.org/10.1007/s00415-020-10201-1

Auteurs

R Acampora (R)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy. roberto.acampora3@virgilio.it.

A de Falco (A)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.

F Lanfranchi (F)

Department of Health Sciences (DISSAL), University of Genoa, 16132, Genoa, Italy.

S Montella (S)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.

R Scala (R)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.

M Lieto (M)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.

L Durante (L)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.

R Bruno (R)

Department of Neurology and Stroke Unit, Ospedale del Mare Hospital, Naples, Italy.

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