Topical Nerve Growth Factor (NGF) restores electrophysiological alterations in the Ins2

Akita mouse Diabetic retinopathy Electroretinogram Nerve Growth Factor Optical Coherence Tomography Retinal ganglion cells Scotopic Threshold Response

Journal

Experimental eye research
ISSN: 1096-0007
Titre abrégé: Exp Eye Res
Pays: England
ID NLM: 0370707

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 24 07 2023
revised: 02 10 2023
accepted: 24 10 2023
medline: 27 11 2023
pubmed: 28 10 2023
entrez: 27 10 2023
Statut: ppublish

Résumé

People suffering from diabetes mellitus commonly have to face diabetic retinopathy (DR), an eye disease characterized by early retinal neurodegeneration and microvascular damage, progressively leading to sight loss. The Ins2

Identifiants

pubmed: 37890756
pii: S0014-4835(23)00314-7
doi: 10.1016/j.exer.2023.109693
pii:
doi:

Substances chimiques

Ins2 protein, mouse 0
Insulin 0
Nerve Growth Factor 9061-61-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109693

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest PR: licensed intellectual property Dompé Farmaceutici SpA (Milan, Italy). The remaining authors declare that the research was conducted without any conflicts of interest.

Auteurs

Valerio Castoldi (V)

Experimental Neurophysiology Unit, Institute of Experimental Neurology-INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Gianpaolo Zerbini (G)

Complications of Diabetes Unit, Diabetes Research Institute-DRI, IRCCS Ospedale San Raffaele, Milan, Italy.

Silvia Maestroni (S)

Complications of Diabetes Unit, Diabetes Research Institute-DRI, IRCCS Ospedale San Raffaele, Milan, Italy.

Ilaria Viganò (I)

Complications of Diabetes Unit, Diabetes Research Institute-DRI, IRCCS Ospedale San Raffaele, Milan, Italy.

Paolo Rama (P)

Cornea and Ocular Surface Unit, IRCCS Ospedale San Raffaele, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.

Letizia Leocani (L)

Experimental Neurophysiology Unit, Institute of Experimental Neurology-INSPE, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy. Electronic address: leocani.letizia@unisr.it.

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Classifications MeSH