Nontuberculous Mycobacterial Pulmonary Disease in the Immunocompromised Host.

HIV Immunocompromised host Immunosuppressive agents Mycobacterium infections Nontuberculous Nontuberculous mycobacteria Organ transplantation Transplant recipients

Journal

Clinics in chest medicine
ISSN: 1557-8216
Titre abrégé: Clin Chest Med
Pays: United States
ID NLM: 7907612

Informations de publication

Date de publication:
12 2023
Historique:
medline: 30 10 2023
pubmed: 28 10 2023
entrez: 27 10 2023
Statut: ppublish

Résumé

The immunocompromised host is at an increased risk for pulmonary and extrapulmonary NTM infections. Where data are available in these specific populations, increased mortality is observed with NTM disease. Prior to starting therapy for NTM disease, providers should ensure diagnostic criteria are met as treatment is long and often associated with significant side effects and toxicities. Treatment should involve 2 to 4 agents and be guided by cultures and antimicrobial susceptibilities. Drug interactions are important to consider, especially in those with HIV or transplant recipients. Whenever possible, immunosuppression should be reduced or changed.

Identifiants

pubmed: 37890919
pii: S0272-5231(23)00048-5
doi: 10.1016/j.ccm.2023.06.007
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

829-838

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Cara D Varley (CD)

Department of Medicine, Division of Infectious Diseases, Oregon Health & Science University; Program in Epidemiology, Oregon Health & Science University-Portland State University School of Public Health. Electronic address: varleyc@ohsu.edu.

Amber C Streifel (AC)

Department of Pharmacy Services, Oregon Health & Science University.

Amanda M Bair (AM)

Department of Pharmacy Services, Oregon Health & Science University.

Kevin L Winthrop (KL)

Department of Medicine, Division of Infectious Diseases, Oregon Health & Science University; Program in Epidemiology, Oregon Health & Science University-Portland State University School of Public Health.

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Classifications MeSH