Rheuma-VOR study: optimising healthcare of rheumatic diseases by multiprofessional coordinating centres.

arthritis, psoriatic arthritis, rheumatoid health services research spondylitis, ankylosing

Journal

Annals of the rheumatic diseases
ISSN: 1468-2060
Titre abrégé: Ann Rheum Dis
Pays: England
ID NLM: 0372355

Informations de publication

Date de publication:
26 Nov 2023
Historique:
received: 25 03 2023
accepted: 04 09 2023
pubmed: 28 10 2023
medline: 28 10 2023
entrez: 27 10 2023
Statut: aheadofprint

Résumé

Early diagnosis of inflammatory arthritis is critical to prevent joint damage and functional incapacities. However, the discrepancy between recommendations of early diagnosis and reality is remarkable. The Rheuma-VOR study aimed to improve the time to diagnosis of patients with early arthritis by coordinating cooperation between primary care physicians, specialists and patients in Germany. This prospective non-randomised multicentre study involved 2340 primary care physicians, 72 rheumatologists, 4 university hospitals and 4 rheumatology centres in 4 German Federal States. The two coprimary endpoints (time to diagnosis and screening performance of primary care physicians) were evaluated for early versus late implementation phase. Additionally, time to diagnosis and secondary endpoints (decrease of disease activity, increase in quality of life and overall well-being, improvement of fatigue, depression, functional ability, and work ability, reduction in drug and medical costs and hospitalisation) were compared with a reference cohort of the German Rheumatism Research Centre (DRFZ) reflecting standard care. A total of 7049 patients were enrolled in the coordination centres and 1537 patients were diagnosed with a rheumatic disease and consented to further participation. A follow-up consultation after 1 year was realised in 592 patients. The time to diagnosis endpoint and the secondary endpoints were met. In addition, the calculation of cost-effectiveness shows that Rheuma-VOR has a dominant cost-benefit ratio compared with standard care. Rheuma-VOR has shown an improvement in rheumatological care, patient-reported outcome parameters and cost savings by coordinating the cooperation of primary care physicians, rheumatologists and patients, in a nationwide approach.

Identifiants

pubmed: 37890976
pii: ard-2023-224205
doi: 10.1136/ard-2023-224205
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Matthias Dreher (M)

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Torsten Witte (T)

Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany.

Kirsten Hoeper (K)

Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany.
Center for Rheumatology Lower Saxony, Hannover, Germany.

Gunter Assmann (G)

Center of Rheumatology and Clinical Immunology, RUB-University Hospital Minden JWK, Minden, Germany.

Fabian Proft (F)

Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charite Universitatsmedizin Berlin, Berlin, Germany.

Denis Poddubnyy (D)

Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charite Universitatsmedizin Berlin, Berlin, Germany.

Niels Murawski (N)

Internal Medicine I Oncology, Haematology, Clinical Immunology and Clinical Rheumatology, Saarland University Hospital and Saarland University Faculty of Medicine, Homburg, Germany.

Konstantinos Triantafyllias (K)

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Center for Rheumatology Rhineland-Palatinate, Bad Kreuznach, Germany.

Marlon Grodd (M)

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

Erika Graf (E)

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

Urs A Fichtner (UA)

Institute of Medical Biometry and Statistics, Section of Healthcare Research and Rehabilitation Research, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

Harald Binder (H)

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

Jan Zeidler (J)

Center for Health Economics Research Hannover (CHERH), Leibniz Universitat Hannover, Hannover, Germany.

Juliana Rachel Hoeper (JR)

Center for Health Economics Research Hannover (CHERH), Leibniz Universitat Hannover, Hannover, Germany.

Johanna Callhoff (J)

Epidemiology and Health Services Research, German Rheumatism Research Centre, Berlin, Germany.
Institute for Social Medicine, Epidemiology and Health Economics, Charite Universitatsmedizin Berlin, Berlin, Germany.

Kirsten Karberg (K)

Center for Rheumatology Berlin, Berlin, Germany.

Anna Trautwein (A)

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Dativa Tibyampansha (D)

Department of Pharmacolgy, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Leszek Wojnowski (L)

Department of Pharmacolgy, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

Reinhold E Schmidt (RE)

Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany.

Andreas Schwarting (A)

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine I, University Medical Center of the Johannes Gutenberg University, Mainz, Germany schwarting@uni-mainz.de.
Center for Rheumatology Rhineland-Palatinate, Bad Kreuznach, Germany.

Classifications MeSH