Spatio-temporal analysis of sheep and goat pox outbreaks in Uganda during 2011-2022.
Active surveillance
Goat pox virus [GTPV]
Passive surveillance
Reporting
SGP antibodies
Sheep and goat pox
Sheep and goat pox [SGP]
Sheep pox virus [SPPV]
Journal
BMC veterinary research
ISSN: 1746-6148
Titre abrégé: BMC Vet Res
Pays: England
ID NLM: 101249759
Informations de publication
Date de publication:
28 Oct 2023
28 Oct 2023
Historique:
received:
22
11
2022
accepted:
17
10
2023
medline:
30
10
2023
pubmed:
28
10
2023
entrez:
27
10
2023
Statut:
epublish
Résumé
Sheep and goat pox (SGP) caused by sheep poxvirus (SPV) and goat poxvirus (GPV) respectively; are transboundary and World Organisation for Animal Health (WOAH)-notifiable viral diseases. There is barely any coherent information about the distribution and prevalence of SGP for Uganda. We therefore conducted this study to describe the temporal and spatial distribution of SGP suspected outbreaks in Uganda for the period 2011-2020 as well as serologically confirm presence of SGP antibodies in suspected SGP outbreaks reported in 2021-2022. Thirty-seven [37] SGP outbreaks were reported across the country during the study period. North-eastern region [that comprises of Karamoja region] had the highest number of outbreaks [n = 17, 45%]; followed by Central [n = 9, 2.4%], Northern [n = 8, 2.2%] and Western region [n = 3, 0.08%]. Reports from district veterinary personnel indicate that the prevalence of; and mortality rate and case fatality rate associated with SGP were 0.06%, 0.02% and 32% respectively. There was a steady increase in the number of reported SGP outbreaks [x̄ = 4] over the study period. Seropositivity of SGPV antibodies in outbreak sheep and goats that were investigated during the study period [2021-2022] was [n = 41, 27%, 95 CI;] CONCLUSION: Our analyses of SGPV passive and active reports indicate that SGP is present in Uganda with a decade long average of four outbreaks per annum. During this period, about a third of all SGPV-clinically infected animals died. SPG is therefore a major constraint to small ruminant health and productivity in Uganda. Introduction of animals from infected herds and breach in farm biosecurity were the most important predictors of SGP outbreaks. In addition to the already existing SGP commercial vaccines, small ruminant screening for SGPV before introducing them to naïve herds and ensuring on farm biosecurity should be part of the SGP control tool pack for Ugandan small ruminant farmers.
Sections du résumé
BACKGROUND
BACKGROUND
Sheep and goat pox (SGP) caused by sheep poxvirus (SPV) and goat poxvirus (GPV) respectively; are transboundary and World Organisation for Animal Health (WOAH)-notifiable viral diseases. There is barely any coherent information about the distribution and prevalence of SGP for Uganda. We therefore conducted this study to describe the temporal and spatial distribution of SGP suspected outbreaks in Uganda for the period 2011-2020 as well as serologically confirm presence of SGP antibodies in suspected SGP outbreaks reported in 2021-2022.
RESULTS
RESULTS
Thirty-seven [37] SGP outbreaks were reported across the country during the study period. North-eastern region [that comprises of Karamoja region] had the highest number of outbreaks [n = 17, 45%]; followed by Central [n = 9, 2.4%], Northern [n = 8, 2.2%] and Western region [n = 3, 0.08%]. Reports from district veterinary personnel indicate that the prevalence of; and mortality rate and case fatality rate associated with SGP were 0.06%, 0.02% and 32% respectively. There was a steady increase in the number of reported SGP outbreaks [x̄ = 4] over the study period. Seropositivity of SGPV antibodies in outbreak sheep and goats that were investigated during the study period [2021-2022] was [n = 41, 27%, 95 CI;] CONCLUSION: Our analyses of SGPV passive and active reports indicate that SGP is present in Uganda with a decade long average of four outbreaks per annum. During this period, about a third of all SGPV-clinically infected animals died. SPG is therefore a major constraint to small ruminant health and productivity in Uganda. Introduction of animals from infected herds and breach in farm biosecurity were the most important predictors of SGP outbreaks. In addition to the already existing SGP commercial vaccines, small ruminant screening for SGPV before introducing them to naïve herds and ensuring on farm biosecurity should be part of the SGP control tool pack for Ugandan small ruminant farmers.
Identifiants
pubmed: 37891597
doi: 10.1186/s12917-023-03788-w
pii: 10.1186/s12917-023-03788-w
pmc: PMC10612334
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
224Informations de copyright
© 2023. The Author(s).
Références
Prev Vet Med. 2021 Nov;196:105473
pubmed: 34479042
Virology. 2008 Feb 20;371(2):380-93
pubmed: 17988703
Transbound Emerg Dis. 2017 Jun;64(3):729-745
pubmed: 26564428
Transbound Emerg Dis. 2022 Sep;69(5):e1642-e1658
pubmed: 35231154
Heliyon. 2022 Jun 06;8(6):e09674
pubmed: 35711991
Trop Anim Health Prod. 2013 Jan;45(1):35-43
pubmed: 22956440
Prev Vet Med. 2019 Nov 1;171:104766
pubmed: 31541845
Vet Med Int. 2021 Jan 5;2021:6629510
pubmed: 33489079
BMC Vet Res. 2017 Dec 11;13(1):385
pubmed: 29228958
Anim Dis. 2021;1(1):28
pubmed: 34806086
Prev Vet Med. 2022 Jan;198:105503
pubmed: 34808578
Virus Genes. 2014 Oct;49(2):286-91
pubmed: 24952423
BMC Vet Res. 2021 Mar 8;17(1):115
pubmed: 33685458
Front Vet Sci. 2020 Jan 29;7:8
pubmed: 32083098
Vet Med (Auckl). 2021 Dec 07;12:303-315
pubmed: 34909409
EFSA J. 2021 Dec 27;19(12):e06933
pubmed: 34963791
Vet Med Sci. 2019 Aug;5(3):412-418
pubmed: 30993915
Microorganisms. 2021 Apr 23;9(5):
pubmed: 33922409
Virusdisease. 2014 Jan;25(1):39-56
pubmed: 24426309
Vet Microbiol. 2013 Jul 26;165(1-2):38-44
pubmed: 23313537
Aust Vet J. 2005 Aug;83(8):466-7
pubmed: 16119417