Circulating Small Extracellular Vesicles Reflect the Severity of Myocardial Damage in STEMI Patients.

Humans ST Elevation Myocardial Infarction Myocardium / pathology Magnetic Resonance Imaging Percutaneous Coronary Intervention Inflammation / pathology

cardiac magnetic resonance microvascular obstruction myocardial infarction platelets small extracellular vesicles

Journal

Biomolecules

ISSN: 2218-273X

Titre abrégé: Biomolecules

Pays: Switzerland

ID NLM: 101596414

Informations de publication

Date de publication:
29 09 2023

Historique:

received: 03 08 2023

revised: 15 09 2023

accepted: 28 09 2023

medline: 30 10 2023

pubmed: 28 10 2023

entrez: 28 10 2023

Statut: epublish

Résumé

Circulating small extracellular vesicles (sEVs) contribute to inflammation, coagulation and vascular injury, and have great potential as diagnostic markers of disease. The ability of sEVs to reflect myocardial damage assessed by Cardiac Magnetic Resonance (CMR) in ST-segment elevation myocardial infarction (STEMI) is unknown. To fill this gap, plasma sEVs were isolated from 42 STEMI patients treated by primary percutaneous coronary intervention (pPCI) and evaluated by CMR between days 3 and 6. Nanoparticle tracking analysis showed that sEVs were greater in patients with anterior STEMI (

Identifiants

DOI: 10.3390/biom13101470 PMID: 37892152 PMC: PMC10605123

pubmed: 37892152

pii: biom13101470

doi: 10.3390/biom13101470

pmc: PMC10605123

pii:

doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Références

J Cardiovasc Magn Reson. 2005;7(2):481-5

pubmed: 15881532

Front Immunol. 2022 Apr 04;13:824188

pubmed: 35444652

J Am Coll Cardiol. 2004 Feb 18;43(4):534-41

pubmed: 14975460

Front Pharmacol. 2016 Aug 31;7:293

pubmed: 27630570

J Cardiovasc Magn Reson. 2013 May 01;15:35

pubmed: 23634753

Nucleic Acids Res. 2022 Jan 7;50(D1):D687-D692

pubmed: 34788843

J Am Coll Cardiol. 2010 May 25;55(21):2383-9

pubmed: 20488311

JACC Cardiovasc Imaging. 2014 Sep;7(9):930-9

pubmed: 25212799

Front Oncol. 2021 Oct 20;11:727317

pubmed: 34745949

Int J Mol Sci. 2021 Sep 08;22(18):

pubmed: 34575865

Vascul Pharmacol. 2015 Aug;71:24-30

pubmed: 25869502

J Thromb Thrombolysis. 2021 May;51(4):1138-1143

pubmed: 33043416

J Cardiovasc Magn Reson. 2008 Jul 07;10:35

pubmed: 18605997

Curr Pharm Des. 2013;19(25):4564-75

pubmed: 23270553

J Mol Cell Cardiol. 2020 Jan;138:110-114

pubmed: 31783033

Nat Rev Cardiol. 2023 Apr;20(4):236-247

pubmed: 36316574

Int J Mol Sci. 2021 Jul 28;22(15):

pubmed: 34360827

Biology (Basel). 2021 Jan 30;10(2):

pubmed: 33573196

Eur Heart J. 2011 Jul;32(13):1640-8

pubmed: 21398642

Heart. 2008 Jul;94(7):943-8

pubmed: 18552230

Bioinformatics. 2009 Apr 15;25(8):1091-3

pubmed: 19237447

Nat Rev Cardiol. 2019 Mar;16(3):166-179

pubmed: 30429532

Cell Death Discov. 2022 Nov 26;8(1):467

pubmed: 36435831

Scand J Clin Lab Invest. 2019 Nov;79(7):507-512

pubmed: 31502883

Science. 2020 Feb 7;367(6478):

pubmed: 32029601

Am J Cardiol. 2020 Apr 1;125(7):1013-1019

pubmed: 31955831

Genome Res. 2003 Nov;13(11):2498-504

pubmed: 14597658

Cardiol Res Pract. 2021 May 24;2021:5545416

pubmed: 34123416

JACC Cardiovasc Imaging. 2019 Jun;12(6):1007-1017

pubmed: 29680345

Clin Ther. 2014 Jun 1;36(6):830-46

pubmed: 24952934

Am J Cardiol. 1993 Dec 15;72(18):1366-70

pubmed: 8256728

Thromb Res. 2023 Sep;229:114-126

pubmed: 37437517

J Am Coll Cardiol. 2010 Jun 1;55(22):2459-69

pubmed: 20510213

JACC Cardiovasc Imaging. 2018 Jun;11(6):813-825

pubmed: 28823746

Diagnostics (Basel). 2020 Nov 12;10(11):

pubmed: 33198302

J Am Coll Cardiol. 2000 Oct;36(4):1202-9

pubmed: 11028471