Lanthanide-Based Organic Salts: Synthesis, Characterization, and Cytotoxicity Studies.
MRI contrast agents
cytotoxicity
gadolinium salts
magnetic organic salts
terbium salts
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
18 Oct 2023
18 Oct 2023
Historique:
received:
01
08
2023
revised:
06
09
2023
accepted:
07
09
2023
medline:
30
10
2023
pubmed:
28
10
2023
entrez:
28
10
2023
Statut:
epublish
Résumé
The formulation of magnetic ionic liquids (MILs) or organic salts based on lanthanides as anions has been explored. In this work, a set of choline-family-based salts, and two other, different cation families, were combined with Gadolinium(III) and Terbium(III) anions. Synthetic methodologies were previously optimized, and all organic salts were obtained as solids with melting temperatures higher than 100 °C. The magnetic moments obtained for the Gd(III) salts were, as expected, smaller than those obtained for the Tb(III)-based compounds. The values for Gd(III) and Tb(III) magnetic salts are in the range of 6.55-7.30 MB and 8.22-9.34 MB, respectively. It is important to note a correlation between the magnetic moments obtained for lanthanides, and the structural features of the cation. The cytotoxicity of lanthanide-based salts was also evaluated using 3T3, 293T, Caco2, and HepG2 cells, and it was revealed that most of the prepared compounds are not toxic.
Identifiants
pubmed: 37894633
pii: molecules28207152
doi: 10.3390/molecules28207152
pmc: PMC10608950
pii:
doi:
Substances chimiques
Lanthanoid Series Elements
0
Salts
0
Anions
0
Cations
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
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