In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines.

DNA repair gene azomethine group cytotoxicity gastric cancer gene expression molecular docking

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
28 Sep 2023
Historique:
received: 04 09 2023
revised: 20 09 2023
accepted: 23 09 2023
medline: 28 10 2023
pubmed: 28 10 2023
entrez: 28 10 2023
Statut: epublish

Résumé

We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were synthesized by a condensation reaction and received compounds were characterized by

Identifiants

pubmed: 37895364
pii: life13101982
doi: 10.3390/life13101982
pmc: PMC10607974
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Cancer. 1980 Jul 1;46(1):139-43
pubmed: 6992974
Cancer. 1996 Jun 15;77(12):2449-57
pubmed: 8640692
Cancer Res. 2002 Aug 1;62(15):4499-506
pubmed: 12154061
Mutat Res. 2008 Jul-Aug;659(1-2):49-55
pubmed: 18308619
Curr Opin Pulm Med. 2007 Jul;13(4):284-9
pubmed: 17534174
Springerplus. 2016 Jun 24;5(1):887
pubmed: 27386335
Nat Protoc. 2013 Sep;8(9):1660-9
pubmed: 23928499
Curr Drug Metab. 2008 Feb;9(2):167-74
pubmed: 18288958
J Invest Dermatol. 1997 Jan;108(1):3-6
pubmed: 8980277
Ann Clin Transl Neurol. 2020 Aug;7(8):1443-1449
pubmed: 32627353
Genes Chromosomes Cancer. 2014 Jan;53(1):25-37
pubmed: 24142626
Biomarkers. 2012 Dec;17(8):671-91
pubmed: 22900535
Br J Cancer. 1993 Dec;68(6):1227-31
pubmed: 8260377
DNA Repair (Amst). 2011 Jul 15;10(7):781-91
pubmed: 21612988
Cancer Lett. 2015 Mar 1;358(1):1-7
pubmed: 25528630
J Biol Chem. 2003 Aug 15;278(33):30869-74
pubmed: 12791699
Am J Hum Genet. 2012 Mar 9;90(3):511-7
pubmed: 22341969
Molecules. 2008 Apr 08;13(4):804-11
pubmed: 18463582
Biochem J. 1997 Jul 15;325 ( Pt 2):481-6
pubmed: 9230131
Crit Rev Oncol Hematol. 2009 Aug;71(2):127-64
pubmed: 19230702
Front Biosci (Landmark Ed). 2015 Jun 01;20(8):1234-49
pubmed: 25961554
Am J Hum Genet. 2013 May 2;92(5):807-19
pubmed: 23623389
Spectrochim Acta A Mol Biomol Spectrosc. 2023 Feb 5;286:122006
pubmed: 36283207
Cell Biochem Funct. 2004 Nov-Dec;22(6):343-52
pubmed: 15386533
Br J Cancer Suppl. 1987 Jun;8:96-104
pubmed: 3307879
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Jan 5;244:118829
pubmed: 32858450
Nat Med. 2003 May;9(5):568-74
pubmed: 12692539
Pharmacogenomics J. 2007 Feb;7(1):56-65
pubmed: 16788565
Nat Rev Cancer. 2012 Sep;12(9):587-98
pubmed: 22918414
Semin Cell Dev Biol. 2018 Aug;80:50-64
pubmed: 28587975
Eur J Cancer. 1995 Jul-Aug;31A(7-8):1291-4
pubmed: 7577038
Nat Med. 2017 Jan;23(1):120-127
pubmed: 27869804
J Immunol Methods. 1988 Nov 25;115(1):61-9
pubmed: 3192948
Oncogene. 1993 Apr;8(4):933-8
pubmed: 8096076
Cancer Cell. 2015 Feb 9;27(2):211-22
pubmed: 25620030
Cancer Cell. 2014 Feb 10;25(2):166-80
pubmed: 24525233
Chem Cent J. 2015 May 10;9:25
pubmed: 25995769
Surg Today. 2011 Jan;41(1):24-38
pubmed: 21191688
Gastroenterology. 2005 May;128(6):1567-78
pubmed: 15887152
Anticancer Res. 2008 Nov-Dec;28(6B):3921-8
pubmed: 19192650
Cancer Lett. 2010 Sep 28;295(2):144-53
pubmed: 20488613
Curr Mol Pharmacol. 2012 Jan;5(1):115-24
pubmed: 22122468
Cancer Lett. 2018 Oct 1;433:33-42
pubmed: 29959055
Crit Rev Clin Lab Sci. 2006;43(2):143-81
pubmed: 16517421
J Transl Med. 2013 Feb 11;11:36
pubmed: 23398928
Biochim Biophys Acta. 1999 Mar 19;1444(3):395-406
pubmed: 10095062
Spectrochim Acta A Mol Biomol Spectrosc. 2019 Sep 5;220:117102
pubmed: 31146207
Molecules. 2019 Aug 28;24(17):
pubmed: 31466322
J Biochem Mol Toxicol. 2022 May;36(5):e23018
pubmed: 35199412
Chest. 2005 Mar;127(3):978-83
pubmed: 15764785
Cancer Cell. 2006 Sep;10(3):241-52
pubmed: 16959615
Am J Pathol. 2000 Mar;156(3):839-47
pubmed: 10702400
Int J Oncol. 2018 Mar;52(3):656-678
pubmed: 29286103
Bioorg Med Chem Lett. 2010 Apr 15;20(8):2417-20
pubmed: 20346660
Environ Mol Mutagen. 2017 Jun;58(5):235-263
pubmed: 28485537
Dalton Trans. 2013 Nov 28;42(44):15678-86
pubmed: 24048480
Annu Rev Biochem. 2004;73:39-85
pubmed: 15189136
Genes Chromosomes Cancer. 2004 Apr;39(4):288-97
pubmed: 14978790
Cancer Cell. 2008 Dec 9;14(6):458-70
pubmed: 19061837
FASEB J. 2003 Jul;17(10):1195-214
pubmed: 12832285
J Biol Chem. 2005 Jan 14;280(2):1186-92
pubmed: 15533933

Auteurs

Alpaslan Ozturk (A)

Clinical Biochemistry, Etlik City Hospital, 06170 Ankara, Turkey.

Tugba Agbektas (T)

Department of Food Processing Technologies Services, Yıldızeli Vocational School, 58500 Sivas, Turkey.

Alakbar Huseynzada (A)

Industrial Chemistry Research Laboratory, Baku State University, Z. Khalilov 33, Baku AZ1148, Azerbaijan.
GPOGC SRI, Azerbaijan State Oil and Industry University, Baku AZ1010, Azerbaijan.
Department of Chemistry, Azerbaijan Engineers Union, Bashir Safaroglu 118, Baku AZ1022, Azerbaijan.
ICESCO Biomedical Materials Department, Baku State University, Z. Khalilov 33, Baku AZ1148, Azerbaijan.

Ruslan Guliyev (R)

Industrial Chemistry Research Laboratory, Baku State University, Z. Khalilov 33, Baku AZ1148, Azerbaijan.
GPOGC SRI, Azerbaijan State Oil and Industry University, Baku AZ1010, Azerbaijan.

Rana Ganbarova (R)

Industrial Chemistry Research Laboratory, Baku State University, Z. Khalilov 33, Baku AZ1148, Azerbaijan.
GPOGC SRI, Azerbaijan State Oil and Industry University, Baku AZ1010, Azerbaijan.

Ulviyya Hasanova (U)

Industrial Chemistry Research Laboratory, Baku State University, Z. Khalilov 33, Baku AZ1148, Azerbaijan.
GPOGC SRI, Azerbaijan State Oil and Industry University, Baku AZ1010, Azerbaijan.
ICESCO Biomedical Materials Department, Baku State University, Z. Khalilov 33, Baku AZ1148, Azerbaijan.

Ayca Tas (A)

Department of Nutrition and Diet, Faculty of Health Sciences, Sivas Cumhuriyet University, 58140 Sivas, Turkey.

Sultan Erkan (S)

Department of Chemistry, Faculty of Science, Sivas Cumhuriyet University, 58140 Sivas, Turkey.

Cemile Zontul (C)

Department of Chemistry and Chemical Processing Technologies Services, Yıldızeli Vocational School, 58500 Sivas, Turkey.

Nihal Inandiklioglu (N)

Department of Medical Biology, Faculty of Medicine, Yozgat Bozok University, 66100 Yozgat, Turkey.

Yavuz Silig (Y)

Department of Biochemistry, Faculty of Medicine, Sivas Cumhuriyet University, 58140 Sivas, Turkey.

Classifications MeSH