Novel Remineralizing and Antibiofilm Low-Shrinkage-Stress Nanocomposites to Inhibit Salivary Biofilms and Protect Tooth Structures.

amorphous calcium phosphate nanoparticles antibiofilm calcium fluoride nanoparticles caries dimethylaminododecyl methacrylate remineralizing

Journal

Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929

Informations de publication

Date de publication:
19 Oct 2023
Historique:
received: 14 09 2023
revised: 02 10 2023
accepted: 12 10 2023
medline: 28 10 2023
pubmed: 28 10 2023
entrez: 28 10 2023
Statut: epublish

Résumé

Recurrent caries remain a persistent concern, often linked to microleakage and a lack of bioactivity in contemporary dental composites. Our study aims to address this issue by developing a low-shrinkage-stress nanocomposite with antibiofilm and remineralization capabilities, thus countering the progression of recurrent caries. In the present study, we formulated low-shrinkage-stress nanocomposites by combining triethylene glycol divinylbenzyl ether and urethane dimethacrylate, incorporating dimethylaminododecyl methacrylate (DMADDM), along with nanoparticles of calcium fluoride (nCaF

Identifiants

pubmed: 37895752
pii: ma16206770
doi: 10.3390/ma16206770
pmc: PMC10608551
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : University of Maryland, Baltimore
ID : Seed Grant
Organisme : University of Maryland School of Dentistry
ID : Bridge Funding

Références

Dent Mater. 2011 Jun;27(6):509-19
pubmed: 21388669
Dent Mater. 2012 Jun;28(6):642-52
pubmed: 22429937
Biomaterials. 2004 Nov;25(24):5467-72
pubmed: 15142727
Acta Biomater. 2017 Feb;49:16-35
pubmed: 27845274
Materials (Basel). 2021 Aug 27;14(17):
pubmed: 34500955
Braz Oral Res. 2013 Mar-Apr;27(2):97-102
pubmed: 23459774
Int J Prosthodont. 1997 Nov-Dec;10(6):513-9
pubmed: 9495171
J Dent Res. 2020 Feb;99(2):189-195
pubmed: 31861961
Dent Mater. 2015 Nov;31(11):e247-77
pubmed: 26410151
Dent Mater. 2012 Feb;28(2):219-28
pubmed: 22035983
PLoS One. 2018 Feb 21;13(2):e0191942
pubmed: 29466366
J Biomed Mater Res. 1998 Mar 15;39(4):511-5
pubmed: 9492208
Braz Oral Res. 2017 Aug 28;31(suppl 1):e62
pubmed: 28902242
Oper Dent. 2016 Sep-Oct;41(5):491-500
pubmed: 26794188
J Dent. 2013 Jun;41(6):504-13
pubmed: 23583528
Braz Oral Res. 2009;23 Suppl 1:23-30
pubmed: 19838555
Dent Mater. 2015 Nov;31(11):1279-89
pubmed: 26361809
J Dent. 2018 May;72:1-7
pubmed: 29522787
Oper Dent. 2014 Mar-Apr;39(2):E71-82
pubmed: 24147769
J Clin Med. 2022 Nov 07;11(21):
pubmed: 36362817
J Dent Res. 2017 Apr;96(4):364-371
pubmed: 28318391
Int J Environ Res Public Health. 2020 Nov 19;17(22):
pubmed: 33228082
J Funct Biomater. 2023 Jun 25;14(7):
pubmed: 37504831
Trends Biotechnol. 2013 Aug;31(8):459-67
pubmed: 23810638
Caries Res. 2009;43(2):132-6
pubmed: 19321991
Adv Dent Res. 1996 Nov;10(2):225-31
pubmed: 9206341
J Dent. 2022 Sep;124:104218
pubmed: 35817225
Materials (Basel). 2019 Aug 22;12(17):
pubmed: 31443429
Dent Mater. 2005 Dec;21(12):1129-36
pubmed: 16046231
Dent Mater. 2021 Apr;37(4):578-587
pubmed: 33573842
Acta Biomater. 2011 Mar;7(3):1346-53
pubmed: 21050900
Materials (Basel). 2017 Jun 12;10(6):
pubmed: 28773004
Dent Mater. 2018 Jan;34(1):78-96
pubmed: 29179971
Microbiology (Reading). 2008 Nov;154(Pt 11):3247-3255
pubmed: 18957579
Microbiol Spectr. 2019 Jan;7(1):
pubmed: 30657107
Dent Mater. 2009 Apr;25(4):424-30
pubmed: 19019421
Dent Mater. 2005 Oct;21(10):962-70
pubmed: 16085301
Int Dent J. 2000 Dec;50(6):361-6
pubmed: 11197194
Oper Dent. 2015 Sep-Oct;40(5):E206-21
pubmed: 26237639
Dent Mater J. 2009 Jan;28(1):11-9
pubmed: 19280964
Dent Mater. 2005 Jan;21(1):36-42
pubmed: 15681000
J Dent Res. 1998 Jan;77(1):60-7
pubmed: 9437400
Dent Mater. 2013 Aug;29(8):859-70
pubmed: 23768794
Acta Biomater. 2012 Nov;8(11):4151-61
pubmed: 22842038
J Funct Biomater. 2020 Aug 01;11(3):
pubmed: 32752248
Microbiol Rev. 1986 Dec;50(4):353-80
pubmed: 3540569
Rambam Maimonides Med J. 2021 Jan 19;12(1):
pubmed: 33478627
Front Microbiol. 2021 Feb 02;12:636684
pubmed: 33603728
Odontology. 2006 Sep;94(1):1-9
pubmed: 16998612
Dent Mater. 2005 Dec;21(12):1137-43
pubmed: 16046232
Bioengineering (Basel). 2023 Aug 22;10(9):
pubmed: 37760093
Dent J (Basel). 2021 Aug 03;9(8):
pubmed: 34436000
Dent Mater. 2003 Sep;19(6):558-66
pubmed: 12837405
J Dent. 2012 May;40(5):359-63
pubmed: 22326721
Dent Mater. 2003 Jun;19(4):313-9
pubmed: 12686296
Dent Mater. 2014 Mar;30(3):249-62
pubmed: 24444789
Int J Clin Pediatr Dent. 2019 Mar-Apr;12(2):139-144
pubmed: 31571787
Polymers (Basel). 2021 May 14;13(10):
pubmed: 34069312
Curr Pharm Biotechnol. 2013;14(11):960-6
pubmed: 24372246
Radiother Oncol. 2018 Oct;129(1):30-37
pubmed: 29519627
Dent Mater. 2018 May;34(5):693-694
pubmed: 29571660
Biomaterials. 2006 Jul;27(21):3995-4002
pubmed: 16564083

Auteurs

Abdullah Alhussein (A)

PhD Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh 11451, Saudi Arabia.

Rashed Alsahafi (R)

Department of Restorative Dental Sciences, Umm Al-Qura University, College of Dentistry, Makkah 24211, Saudi Arabia.

Areej Alfaifi (A)

PhD Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.
Department of Restorative and Prosthetic Dental Sciences, College of Dentistry King Saud bin Abdulaziz University for Health Sciences, Riyadh 14611, Saudi Arabia.

Mohammad Alenizy (M)

PhD Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.

Ibrahim Ba-Armah (I)

PhD Program in Dental Biomedical Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.

Abraham Schneider (A)

Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.

Mary-Ann Jabra-Rizk (MA)

Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, MD 21201, USA.

Radi Masri (R)

Biomaterials & Tissue Engineering Division, Department of Advanced Oral Sciences and Therapeutics, University Maryland School of Dentistry, Baltimore, MD 21201, USA.

Guadalupe Garcia Fay (G)

Biomaterials & Tissue Engineering Division, Department of Advanced Oral Sciences and Therapeutics, University Maryland School of Dentistry, Baltimore, MD 21201, USA.

Thomas W Oates (TW)

Biomaterials & Tissue Engineering Division, Department of Advanced Oral Sciences and Therapeutics, University Maryland School of Dentistry, Baltimore, MD 21201, USA.

Jirun Sun (J)

The Forsyth Institute, Harvard School of Dental Medicine Affiliate, Cambridge, MA 02142, USA.

Michael D Weir (MD)

Biomaterials & Tissue Engineering Division, Department of Advanced Oral Sciences and Therapeutics, University Maryland School of Dentistry, Baltimore, MD 21201, USA.

Hockin H K Xu (HHK)

Biomaterials & Tissue Engineering Division, Department of Advanced Oral Sciences and Therapeutics, University Maryland School of Dentistry, Baltimore, MD 21201, USA.
Center for Stem Cell Biology & Regenerative Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Classifications MeSH