Systematic reviews and meta-analyses in Homeopathy: Recommendations for summarising evidence from homeopathic intervention studies (Sum-HomIS recommendations).

Evidence Guidelines Homeopathic intervention studies Homeopathy Meta-analysis Research methods Systematic review

Journal

Complementary therapies in medicine
ISSN: 1873-6963
Titre abrégé: Complement Ther Med
Pays: Scotland
ID NLM: 9308777

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 04 05 2023
revised: 16 09 2023
accepted: 23 10 2023
medline: 5 12 2023
pubmed: 29 10 2023
entrez: 28 10 2023
Statut: ppublish

Résumé

Mainly due to the use of different inclusion criteria and quality assessments, systematic reviews (SRs) and meta-analyses (MAs) with homeopathic intervention studies (HOMIS) have shown inconsistent results. We aimed to build recommendations for "Summarizing evidence from Homeopathic Intervention Studies" (Sum-HomIS recommendations) in order to approach standardization. Against the background of a framework-project to update the evidence from homeopathic intervention studies, we launched an expert panel on how to assess the quality of HOMIS and how to summarize evidence from HOMIS. The results of a literature review and the expert communications in advance of the panel as well as the consensus from the discussions are presented here. We added specific considerations for homeopathic veterinary research. On top of the general guidelines when planning a review we report five basic Sum-HomIS recommendations. These are: 1) A broad literature search including special archives and consideration of so-called grey-literature; 2) The inclusion of controlled observational studies alongside randomized controlled trials; 3) The choice of a clear clinical research question in the terms that, if possible, the review project includes studies with predominantly homogeneous populations, interventions, comparators and outcomes (PICOs); 4) The use of a global quality assessment including the assessment of external, model and internal validity; 5) A summary of evidence using the GRADE-approach if the body of evidence is sufficiently large and homogenous or a descriptive summary if it is not so. We present recommendations for designing, conducting, and reporting SRs and MAs with HOMIS.

Sections du résumé

BACKGROUND BACKGROUND
Mainly due to the use of different inclusion criteria and quality assessments, systematic reviews (SRs) and meta-analyses (MAs) with homeopathic intervention studies (HOMIS) have shown inconsistent results. We aimed to build recommendations for "Summarizing evidence from Homeopathic Intervention Studies" (Sum-HomIS recommendations) in order to approach standardization.
METHODS METHODS
Against the background of a framework-project to update the evidence from homeopathic intervention studies, we launched an expert panel on how to assess the quality of HOMIS and how to summarize evidence from HOMIS. The results of a literature review and the expert communications in advance of the panel as well as the consensus from the discussions are presented here. We added specific considerations for homeopathic veterinary research.
RESULTS RESULTS
On top of the general guidelines when planning a review we report five basic Sum-HomIS recommendations. These are: 1) A broad literature search including special archives and consideration of so-called grey-literature; 2) The inclusion of controlled observational studies alongside randomized controlled trials; 3) The choice of a clear clinical research question in the terms that, if possible, the review project includes studies with predominantly homogeneous populations, interventions, comparators and outcomes (PICOs); 4) The use of a global quality assessment including the assessment of external, model and internal validity; 5) A summary of evidence using the GRADE-approach if the body of evidence is sufficiently large and homogenous or a descriptive summary if it is not so.
CONCLUSIONS CONCLUSIONS
We present recommendations for designing, conducting, and reporting SRs and MAs with HOMIS.

Identifiants

pubmed: 37898390
pii: S0965-2299(23)00086-9
doi: 10.1016/j.ctim.2023.102999
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102999

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest Authors declare none.

Auteurs

Katharina Gaertner (K)

Institute of Integrative Medicine, University of Witten/Herdecke, Gerhard-Kienle-Weg 4, DE-58313 Herdecke, Germany.

Susanne Ulbrich-Zürni (S)

WissHom: Scientific Society for Homeopathy, Wallstraße 48, DE-06366 Koethen, Germany.

Stephan Baumgartner (S)

Institute of Complementary and Integrative Medicine IKIM, University of Bern, Freiburgstr. 46, CH-3010 Bern, Switzerland.

Harald Walach (H)

Next Society Institute, Kazimieras Simonavicius University, Vilnius, Lituania; Change Health Institute, Berlin, Germany.

Michael Frass (M)

WissHom: Scientific Society for Homeopathy, Wallstraße 48, DE-06366 Koethen, Germany; em. Medical University of Vienna, Department of Medicine I, A-1090 Vienna, Austria; Institute for Homeopathic Research, Columbusgasse 20, A-1100 Vienna, Austria.

Petra Weiermayer (P)

WissHom: Scientific Society for Homeopathy, Wallstraße 48, DE-06366 Koethen, Germany. Electronic address: forschung@wisshom.de.

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Classifications MeSH