The Effect of Local Tranexamic Acid Administration on Blood Loss and Transfusion in Total Knee Arthroplasty: A Retrospective Study.
Blood transfusion
hemoglobin
surgical drain
total knee arthroplasty
tranexamic acid
Journal
Sisli Etfal Hastanesi tip bulteni
ISSN: 1302-7123
Titre abrégé: Sisli Etfal Hastan Tip Bul
Pays: Turkey
ID NLM: 9424130
Informations de publication
Date de publication:
2023
2023
Historique:
received:
18
04
2023
revised:
23
05
2023
accepted:
23
05
2023
medline:
30
10
2023
pubmed:
30
10
2023
entrez:
30
10
2023
Statut:
epublish
Résumé
The standard surgical method for primary gonarthrosis in advanced stages is total knee arthroplasty (TKA), despite the risk of bleeding that requires transfusion. Blood transfusions are potentially dangerous. The aim of this study was to determine whether there is a statistical difference in the amount of bleeding and the need for transfusion between patients who received and did not receive perioperative local tranexamic acid in TKA. The hospital data system was used to access the data of patients who underwent TKA in our clinic between January 2015 and January 2022 with a diagnosis of gonarthrosis. Patients who underwent TKA and had gonarthrosis as the primary diagnosis were included in the study. They were separated into two groups: A control group (Group C) and a group that received perioperative local tranexamic acid (Group LTXA). The amount of bleeding was compared by taking into account patients' hemogram follow-ups, the amount of blood from their drains, and their transfusion needs during the postoperative period. The findings demonstrated that TKA patients who received local tranexamic acid administration experienced a significant decrease in perioperative blood loss and needed lesser transfusions. The findings of our investigation are consistent with other studies and are in favor of the usage of TXA in TKA. To validate our findings and establish the ideal TXA dosage and administration method in TKA, additional research is required.
Identifiants
pubmed: 37899805
doi: 10.14744/SEMB.2023.42800
pii: SEMB-57-245
pmc: PMC10600620
doi:
Types de publication
Journal Article
Langues
eng
Pagination
245-249Informations de copyright
©Copyright 2023 by The Medical Bulletin of Sisli Etfal Hospital.
Déclaration de conflit d'intérêts
None declared.
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