Hard-to-treat or hard-to-catch? Clinical features and therapeutic outcomes of help-seeking foster care youths with mood disorders.

adverse chilhood experiences child adversity complex psychotrauma depressive disorder developmental psychotrauma disruptive mood dysregulation disorder early-onset bipolar disorder

Journal

Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006

Informations de publication

Date de publication:
2023
Historique:
received: 24 04 2023
accepted: 02 10 2023
medline: 30 10 2023
pubmed: 30 10 2023
entrez: 30 10 2023
Statut: epublish

Résumé

The high level of emotional problems in youths placed in foster care contrasts with the limited use of evidence-based treatments. This study aims to better characterize the clinical features and therapeutic outcomes of foster care youths with mood disorders. A secondary analysis of data collected in the context of a French-Canadian clinical research network on pediatric mood disorders in four sites was conducted to compare three groups of patients with depressive or bipolar disorder: those without exposure to child welfare intervention (WCWI, We observed a very high rate of academic problems in patients in the groups NPI/PI compared to those in the WCWI group. Patients in the PI group had more disruptive behavioral disorders (OR = 6.87, 95% CI [3.25-14.52]), trauma-related disorders (OR = 3.78, 95% CI [1.6-8.94]), and any neurodevelopmental disorders (OR = 2.73, 95% CI [1.36-5.49]) compared to the other groups (NPI/WCWI). Among inpatients, the Clinical Global Impression-Improvement scale and the change in the Children Global Assessment Scale during the hospital stay did not differ across the three groups. We observed a higher prescription rate of antipsychotics in the PI group compared to the NPI/WCWI groups, but no significant difference for antidepressants and mood stabilizers. These findings support the view that, when provided with dedicated support, fostered inpatient youths can improve in a range comparable to other inpatients. Undetected neurodevelopmental disorders and academic problems are likely important contributors of the burden of mood disorders in these youths.

Identifiants

pubmed: 37900296
doi: 10.3389/fpsyt.2023.1211516
pmc: PMC10603296
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1211516

Informations de copyright

Copyright © 2023 Benarous, Lahaye, Pellerin, Consoli, Cohen, Labelle, Renaud, Gérardin, El-Khoury, van der Waerden and Guilé.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Xavier Benarous (X)

Department of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
INSERM Unit U1105 Research Group for Analysis of the Multimodal Cerebral Function, University of Picardy Jules Verne (UPJV), Amiens, France.

Hélène Lahaye (H)

Department of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
INSERM Unit U1105 Research Group for Analysis of the Multimodal Cerebral Function, University of Picardy Jules Verne (UPJV), Amiens, France.

Hugues Pellerin (H)

Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, APHP, Paris, France.

Angèle Consoli (A)

Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, APHP, Paris, France.

David Cohen (D)

Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, APHP, Paris, France.
CNRS UMR 7222, Institute for Intelligent Systems and Robotics, Sorbonne University, Paris, France.

Réal Labelle (R)

Department of Psychology, Université du Québec à Montréal, Montréal, QC, Canada.
Centre for Research and Intervention on Suicide, Ethical Issues and End-of-Life Practices, Université du Québec à Montréal, Montréal, QC, Canada.

Johanne Renaud (J)

Manulife Centre for Breakthroughs in Teen Depression and Suicide Prevention, Douglas Mental Health University Institute, McGill University, Montréal, QC, Canada.
Department of Psychiatry, McGill University, Montréal, QC, Canada.

Priscille Gérardin (P)

Department of Child and Adolescent Psychopathology, Rouen University Hospital, Rouen, France.

Fabienne El-Khoury (F)

Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe de Recherche en Epidémiologie Sociale, Paris, France.

Judith van der Waerden (J)

Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe de Recherche en Epidémiologie Sociale, Paris, France.

Jean-Marc Guilé (JM)

Department of Child and Adolescent Psychopathology, Amiens University Hospital, Amiens, France.
INSERM Unit U1105 Research Group for Analysis of the Multimodal Cerebral Function, University of Picardy Jules Verne (UPJV), Amiens, France.
Pôle de psychiatrie de l'enfant et de l'adolescent, Etablissement Publique de Santé Mentale de la Somme, Paris, France.

Classifications MeSH