Myasthenia Gravis Presenting as Bulbar Palsy.

auto-immune diseases bulbar palsy myasthenia gravis (mg) neuromuscular junction disorders thymoma

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Sep 2023
Historique:
accepted: 22 09 2023
medline: 30 10 2023
pubmed: 30 10 2023
entrez: 30 10 2023
Statut: epublish

Résumé

Myasthenia gravis is a rare autoimmune condition that affects postsynaptic cholinergic receptors, resulting in symptoms of muscular fatigue. Clinical signs could be subtle and variable, often leading to many differentials. This leads to inappropriate tests being performed and a delay in diagnosis. Although ocular signs are more common, it may rarely present as bulbar palsy. Our patient, in her 30s, was referred to the emergency department after six months of symptom onset when she was discovered to be at a high risk of silent aspiration. Her presentation was predominantly bulbar palsy, but after appropriate tests, she was eventually diagnosed with generalized myasthenia gravis with a concurrent thymoma. Her treatment included pyridostigmine, corticosteroid, and immunoglobulins, while a thymectomy was scheduled as a planned procedure. Prompt diagnosis and timely management can reduce morbidity and mortality in such cases.

Identifiants

pubmed: 37900462
doi: 10.7759/cureus.46082
pmc: PMC10611170
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e46082

Informations de copyright

Copyright © 2023, Gosain et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Dhruv Gosain (D)

General Internal Medicine, Peterborough City Hospital, Peterborough, GBR.

Tapas Das (T)

Gastroenterology, Peterborough City Hospital, Peterborough, GBR.

Classifications MeSH