The outcome of acute leukemia patients with SET-NUP214 fusion after allogeneic stem cell transplantation.
SET-CAN/NUP214 fusion
acute T lymphoblastic leukemia
acute myeloid leukemia
allogeneic stem cell transplanation
del(9q)
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2023
2023
Historique:
received:
10
07
2023
accepted:
25
09
2023
medline:
30
10
2023
pubmed:
30
10
2023
entrez:
30
10
2023
Statut:
epublish
Résumé
SET-NUP214 fusion gene, also known as TAF-1-CAN and SET-CAN, is observed in acute myeloid leukemia (AML) and T-cell lymphoblastic leukemia (T-ALL). SET-NUP214 fusion in T-cell lymphoblastic leukemia is associated with chemotherapy resistance, but the prognosis of patients with AML with SET-NUP214 has rarely been reported. In the present study, we retrospectively analyzed all patients with acute leukemia including AML and T-ALL patients with SET-NUP214 fusion who underwent allogeneic stem cell transplantation (alloHSCT) in our center from July 2017 to November 2022. Of the total 11 patients, 5 patients were diagnosed with AML and 6 patients were diagnosed with T-ALL
Identifiants
pubmed: 37901324
doi: 10.3389/fonc.2023.1256043
pmc: PMC10611484
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1256043Informations de copyright
Copyright © 2023 Shen, Yang, Zhang, Chen, Ma, Wei, Zhai, Pang, He, Jiang and Feng.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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