Do community measures impact the effectiveness of a community led HIV testing intervention. Secondary analysis of an HIV self-testing intervention in rural communities in Zimbabwe.


Journal

BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551

Informations de publication

Date de publication:
31 Oct 2023
Historique:
received: 24 03 2023
accepted: 10 10 2023
medline: 2 11 2023
pubmed: 1 11 2023
entrez: 1 11 2023
Statut: epublish

Résumé

There is a growing body of evidence for the role that communities can have in producing beneficial health outcomes. There is also an increasing recognition of the effectiveness and success of community-led interventions to promote public health efforts. This study investigated whether and how community-level measures facilitate a community-led intervention to achieve improved HIV outcomes. This is a secondary analysis of survey data from a cluster randomised trial in 40 rural communities in Zimbabwe. The survey was conducted four months after the intervention was initiated. Communities were randomised 1:1 to either paid distribution arm, where HIV self-test (HIVST) kits were distributed by a paid distributor, or community-led whereby members of the community were responsible for organising and conducting the distribution of HIVST kits. We used mixed effects logistic regression to assess the effect of social cohesion, problem solving, and HIV awareness on HIV testing and prevention. We found no association between community measures and the three HIV outcomes (self-testing, new HIV diagnosis and linkage to VMMC or confirmatory testing). However, the interaction analyses highlighted that in high social cohesion communities, the odds of new HIV diagnosis was greater in the community-led arm than paid distribution arm (OR 2.06 95% CI 1.03-4.19). We found some evidence that community-led interventions reached more undiagnosed people living with HIV in places with high social cohesion. Additional research should seek to understand whether the effect of social cohesion is persistent across other community interventions and outcomes. PACTR201607001701788.

Sections du résumé

BACKGROUND BACKGROUND
There is a growing body of evidence for the role that communities can have in producing beneficial health outcomes. There is also an increasing recognition of the effectiveness and success of community-led interventions to promote public health efforts. This study investigated whether and how community-level measures facilitate a community-led intervention to achieve improved HIV outcomes.
METHODS METHODS
This is a secondary analysis of survey data from a cluster randomised trial in 40 rural communities in Zimbabwe. The survey was conducted four months after the intervention was initiated. Communities were randomised 1:1 to either paid distribution arm, where HIV self-test (HIVST) kits were distributed by a paid distributor, or community-led whereby members of the community were responsible for organising and conducting the distribution of HIVST kits. We used mixed effects logistic regression to assess the effect of social cohesion, problem solving, and HIV awareness on HIV testing and prevention.
RESULTS RESULTS
We found no association between community measures and the three HIV outcomes (self-testing, new HIV diagnosis and linkage to VMMC or confirmatory testing). However, the interaction analyses highlighted that in high social cohesion communities, the odds of new HIV diagnosis was greater in the community-led arm than paid distribution arm (OR 2.06 95% CI 1.03-4.19).
CONCLUSION CONCLUSIONS
We found some evidence that community-led interventions reached more undiagnosed people living with HIV in places with high social cohesion. Additional research should seek to understand whether the effect of social cohesion is persistent across other community interventions and outcomes.
TRIAL REGISTRATION BACKGROUND
PACTR201607001701788.

Identifiants

pubmed: 37907871
doi: 10.1186/s12879-023-08695-x
pii: 10.1186/s12879-023-08695-x
pmc: PMC10617038
doi:

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

974

Subventions

Organisme : World Health Organization
ID : 001
Pays : International

Informations de copyright

© 2023. The Author(s).

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Auteurs

Katherine A Thomas (KA)

London School of Hygiene & Tropical Medicine (LSHTM), London, UK. katherine.thomas1@lshtm.ac.uk.

Euphemia Lindelwe Sibanda (EL)

Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.
Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.

Cheryl Johnson (C)

HIV, Hepatitis and STI Department, World Health Organisation, Geneva, Switzerland.

Constancia Watadzaushe (C)

Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.

Getrude Ncube (G)

Ministry of Health and Child Welfare, Harare, Zimbabwe.

Karin Hatzold (K)

Population Services International, Johannesburg, South Africa.

Mary K Tumushime (MK)

Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.

Miriam Mutseta (M)

Department of Sexual Reproductive Health Rights and Innovations, Population Services International Zimbabwe, Harare, Zimbabwe.

Nancy Ruhode (N)

Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.

Peach P Indravudh (PP)

London School of Hygiene & Tropical Medicine (LSHTM), London, UK.

Frances M Cowan (FM)

Centre for Sexual Health and HIV/AIDS Research (CeSHHAR) Zimbabwe, Harare, Zimbabwe.
Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, UK.

Melissa Neuman (M)

London School of Hygiene & Tropical Medicine (LSHTM), London, UK.

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Classifications MeSH