Vulvo-vaginal epithelial tumors in mares: A preliminary investigation on epithelial-mesenchymal transition and tumor-immune microenvironment.

epithelial-to-mesenchymal transition equus caballus papillomavirus type 2 genital carcinomas horse immunohistochemistry real-time PCR tumor-immune microenvironment

Journal

Veterinary pathology
ISSN: 1544-2217
Titre abrégé: Vet Pathol
Pays: United States
ID NLM: 0312020

Informations de publication

Date de publication:
01 Nov 2023
Historique:
medline: 1 11 2023
pubmed: 1 11 2023
entrez: 1 11 2023
Statut: aheadofprint

Résumé

Vulvo-vaginal epithelial tumors are uncommon in mares, and data on the epithelial-to-mesenchymal transition (EMT) and the tumor-immune microenvironment (TIME) are still lacking. This is a study investigating the equus caballus papillomavirus type 2 (EcPV2) infection state as well as the EMT process and the tumor microenvironment in vulvo-vaginal preneoplastic/ benign (8/22) or malignant (14/22) epithelial lesions in mares. To do this, histopathological, immunohistochemical, transcriptomic,

Identifiants

pubmed: 37909398
doi: 10.1177/03009858231207025
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3009858231207025

Déclaration de conflit d'intérêts

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Auteurs

Federico Armando (F)

University of Veterinary Medicine Hannover, Hannover, Germany.

Ilaria Porcellato (I)

University of Perugia, Perugia, Italy.

Livia de Paolis (L)

University of Perugia, Perugia, Italy.
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Genova, Italy.

Samanta Mecocci (S)

University of Perugia, Perugia, Italy.

Benedetta Passeri (B)

University of Parma, Parma, Italy.

Małgorzata Ciurkiewicz (M)

University of Veterinary Medicine Hannover, Hannover, Germany.

Luca Mechelli (L)

University of Perugia, Perugia, Italy.

Chiara Grazia De Ciucis (C)

Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Genova, Italy.
University of Pavia, Pavia, Italy.

Marzia Pezzolato (M)

Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Genova, Italy.

Floriana Fruscione (F)

Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Genova, Italy.

Chiara Brachelente (C)

University of Perugia, Perugia, Italy.

Vittoria Montemurro (V)

Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Genova, Italy.

Katia Cappelli (K)

University of Perugia, Perugia, Italy.

Christina Puff (C)

University of Veterinary Medicine Hannover, Hannover, Germany.

Wolfgang Baumgärtner (W)

University of Veterinary Medicine Hannover, Hannover, Germany.

Alessandro Ghelardi (A)

Ospedale Apuane, Massa, Italy.

Elisabetta Razzuoli (E)

Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle D'Aosta, Genova, Italy.

Classifications MeSH