Vulvo-vaginal epithelial tumors in mares: A preliminary investigation on epithelial-mesenchymal transition and tumor-immune microenvironment.
epithelial-to-mesenchymal transition
equus caballus papillomavirus type 2
genital carcinomas
horse
immunohistochemistry
real-time PCR
tumor-immune microenvironment
Journal
Veterinary pathology
ISSN: 1544-2217
Titre abrégé: Vet Pathol
Pays: United States
ID NLM: 0312020
Informations de publication
Date de publication:
01 Nov 2023
01 Nov 2023
Historique:
medline:
1
11
2023
pubmed:
1
11
2023
entrez:
1
11
2023
Statut:
aheadofprint
Résumé
Vulvo-vaginal epithelial tumors are uncommon in mares, and data on the epithelial-to-mesenchymal transition (EMT) and the tumor-immune microenvironment (TIME) are still lacking. This is a study investigating the equus caballus papillomavirus type 2 (EcPV2) infection state as well as the EMT process and the tumor microenvironment in vulvo-vaginal preneoplastic/ benign (8/22) or malignant (14/22) epithelial lesions in mares. To do this, histopathological, immunohistochemical, transcriptomic,
Identifiants
pubmed: 37909398
doi: 10.1177/03009858231207025
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3009858231207025Déclaration de conflit d'intérêts
Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.