Chagas disease and perceived quality of life: a cross-sectional study.
Journal
Revista da Sociedade Brasileira de Medicina Tropical
ISSN: 1678-9849
Titre abrégé: Rev Soc Bras Med Trop
Pays: Brazil
ID NLM: 7507456
Informations de publication
Date de publication:
2023
2023
Historique:
received:
04
05
2023
accepted:
29
09
2023
medline:
2
11
2023
pubmed:
1
11
2023
entrez:
1
11
2023
Statut:
epublish
Résumé
Chagas disease (ChD) is a neglected tropical disease that is caused by the protozoan parasite Trypanosoma cruzi and can negatively impact quality of life (QoL). This study aimed to assess and compare QoL between individuals with and without ChD. This cross-sectional study was performed within a concurrent cohort study (REDS). The participants were derived from two blood donation centers: São Paulo capital and Montes Claros, Minas Gerais, Brazil. Participants with ChD were identified in blood donations by serological diagnosis between 2008 and 2010, and those without ChD were donors with negative serology identified during the same period. QoL was assessed using the World Health Organization Quality of Life-BREF questionnaire. Logistic regression was used to compare sociodemographic and clinical characteristics between the groups, and mean, standard deviation, and beta regression were used to compare QoL. In total, 611 individuals participated in the study (328 with ChD and 283 without ChD). Participants with ChD had lower QoL in the physical (p=0.02) and psychological (p<0.01) domains than did individuals without CD. Individuals with ChD had worse QoL perceptions. These results provide a comprehensive understanding of the impact of ChD on individuals' QoL, while also highlighting potential opportunities for improving the care and treatment of those affected.
Sections du résumé
BACKGROUND
BACKGROUND
Chagas disease (ChD) is a neglected tropical disease that is caused by the protozoan parasite Trypanosoma cruzi and can negatively impact quality of life (QoL). This study aimed to assess and compare QoL between individuals with and without ChD.
METHODS
METHODS
This cross-sectional study was performed within a concurrent cohort study (REDS). The participants were derived from two blood donation centers: São Paulo capital and Montes Claros, Minas Gerais, Brazil. Participants with ChD were identified in blood donations by serological diagnosis between 2008 and 2010, and those without ChD were donors with negative serology identified during the same period. QoL was assessed using the World Health Organization Quality of Life-BREF questionnaire. Logistic regression was used to compare sociodemographic and clinical characteristics between the groups, and mean, standard deviation, and beta regression were used to compare QoL.
RESULTS
RESULTS
In total, 611 individuals participated in the study (328 with ChD and 283 without ChD). Participants with ChD had lower QoL in the physical (p=0.02) and psychological (p<0.01) domains than did individuals without CD.
CONCLUSIONS
CONCLUSIONS
Individuals with ChD had worse QoL perceptions. These results provide a comprehensive understanding of the impact of ChD on individuals' QoL, while also highlighting potential opportunities for improving the care and treatment of those affected.
Identifiants
pubmed: 37909506
pii: S0037-86822023000100331
doi: 10.1590/0037-8682-0206-2023
pmc: PMC10615335
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e02062023Références
PLoS Negl Trop Dis. 2020 Jun 29;14(6):e0008399
pubmed: 32598390
Rev Soc Bras Med Trop. 2011 Mar-Apr;44(2):150-6
pubmed: 21556489
Neurol Sci. 2019 Dec;40(12):2595-2601
pubmed: 31363936
Circulation. 2021 Nov 9;144(19):1553-1566
pubmed: 34565171
Circulation. 2013 Mar 12;127(10):1105-15
pubmed: 23393012
Rev Inst Med Trop Sao Paulo. 2021 Apr 23;63:e31
pubmed: 33909845
Infect Dis Clin North Am. 2012 Jun;26(2):275-91
pubmed: 22632639
PLoS Negl Trop Dis. 2020 May 27;14(5):e0008144
pubmed: 32459812
Wkly Epidemiol Rec. 2015 Feb 6;90(6):33-43
pubmed: 25671846
Cien Saude Colet. 2019 Apr;24(4):1405-1416
pubmed: 31066842
Circulation. 2012 May 22;125(20):2454-61
pubmed: 22523306
PLoS Negl Trop Dis. 2018 Nov 1;12(11):e0006814
pubmed: 30383777
Qual Life Res. 2019 Jan;28(1):67-72
pubmed: 30167935
Rev Saude Publica. 2000 Apr;34(2):178-83
pubmed: 10881154
Lancet Infect Dis. 2013 Apr;13(4):342-8
pubmed: 23395248
Rev Port Cardiol (Engl Ed). 2020 May;39(5):279-289
pubmed: 32532535
Am J Trop Med Hyg. 2017 Jun;96(6):1456-1459
pubmed: 28719275
Clin Microbiol Rev. 2019 Nov 27;33(1):
pubmed: 31776135
Acta Trop. 2021 Mar;215:105803
pubmed: 33373585
BMC Infect Dis. 2020 Oct 9;20(1):743
pubmed: 33036559
Glob Heart. 2020 Mar 30;15(1):26
pubmed: 32489799
Lancet. 2010 Apr 17;375(9723):1388-402
pubmed: 20399979
Arq Bras Cardiol. 2011 Apr;96(4):325-31
pubmed: 21359478
Int J Infect Dis. 2020 Feb;91:196-201
pubmed: 31770619
Rev Soc Bras Med Trop. 2016 May-Jun;49(3):319-28
pubmed: 27384829
Trop Med Int Health. 2018 Nov;23(11):1213-1222
pubmed: 30156352
PLoS Negl Trop Dis. 2013;7(2):e2078
pubmed: 23469305
Circulation. 2018 Sep 18;138(12):e169-e209
pubmed: 30354432
BMJ Open. 2017 Jan 16;7(1):e013960
pubmed: 28093440
Parasit Vectors. 2019 Apr 27;12(1):184
pubmed: 31029147
PLoS Negl Trop Dis. 2020 Nov 9;14(11):e0008782
pubmed: 33166280