Pralsetinib in patients with RET fusion-positive non-small cell lung cancer: A plain language summary of the ARROW study.

RET fusion RET inhibition clinical trials frontline therapy lung metastasis non-small cell lung cancer plain language summary targeted therapy

Journal

Future oncology (London, England)
ISSN: 1744-8301
Titre abrégé: Future Oncol
Pays: England
ID NLM: 101256629

Informations de publication

Date de publication:
02 Nov 2023
Historique:
medline: 2 11 2023
pubmed: 2 11 2023
entrez: 2 11 2023
Statut: aheadofprint

Résumé

This is a summary of a research study called ARROW, which tested a medicine called pralsetinib in patients with non-small cell lung cancer (NSCLC), thyroid cancer, and other advanced solid tumours caused by a change in a gene called In total, 281 patients with Overall, the ARROW study showed that pralsetinib was effective in shrinking tumours in patients with

Identifiants

pubmed: 37916501
doi: 10.2217/fon-2023-0155
doi:

Banques de données

ClinicalTrials.gov
['NCT03037385']

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Frank Griesinger (F)

Pius-Hospital, University of Oldenburg, Oldenburg, Germany.

Giuseppe Curigliano (G)

European Institute of Oncology, IRCCS, Milan, Italy.
University of Milano, Milan, Italy.

Vivek Subbiah (V)

Sarah Cannon Research Institute, Nashville, TN, USA.

Christina S Baik (CS)

University of Washington School of Medicine, Seattle, WA, USA.

Daniel Sw Tan (DS)

National Cancer Centre Singapore, Singapore.

Dae H Lee (DH)

Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Daniel Misch (D)

Helios Clinic Emil von Behring, Berlin, Germany.

Elena Garralda (E)

Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.

Dong-Wan Kim (DW)

Seoul National University College of Medicine & Seoul National University Hospital, Seoul, Republic of Korea.

Anthonie J van der Wekken (AJ)

University of Groningen & University Medical Center Groningen, Groningen, Netherlands.

Justin F Gainor (JF)

Massachusetts General Hospital, Boston, MA, USA.

Luis Paz-Ares (L)

Hospital Universitario 12 de Octubre, Madrid, Spain.

Stephen V Liu (SV)

Georgetown University, Washington, DC, USA.

Gregory P Kalemkerian (GP)

University of Michigan, Ann Arbor, MI, USA.

Daniel W Bowles (DW)

University of Colorado School of Medicine, Aurora, CO, USA.

Aaron S Mansfield (AS)

Mayo Clinic, Rochester, NY, USA.

Jessica J Lin (JJ)

Massachusetts General Hospital, Boston, MA, USA.

Vlatka Smoljanovic (V)

F. Hoffmann-La Roche, Ltd, Basel, Switzerland.

Ahmadur Rahman (A)

F. Hoffmann-La Roche, Ltd, Basel, Switzerland.

Alena Zalutskaya (A)

Blueprint Medicines Corporation, Cambridge, MA, USA.

Melinda Louie-Gao (M)

Blueprint Medicines Corporation, Cambridge, MA, USA.

Andy L Boral (AL)

Blueprint Medicines Corporation, Cambridge, MA, USA.

Julien Mazières (J)

Institut Universitaire du Cancer, Toulouse, France.

Classifications MeSH