Asthma incidence can be influenced by climate change in Italy: findings from the GEIRD study-a climatological and epidemiological assessment.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
03 11 2023
Historique:
received: 10 08 2023
accepted: 31 10 2023
medline: 6 11 2023
pubmed: 4 11 2023
entrez: 4 11 2023
Statut: epublish

Résumé

An association between climatic conditions and asthma incidence has been widely assumed. However, it is unclear whether climatic variations have a fingerprint on asthma dynamics over long time intervals. The aim of this study is to detect a possible correlation of the Summer North Atlantic Oscillation (S-NAO) index and the self-calibrated palmer drought severity index (scPDSI) with asthma incidence over the period from 1957 to 2006 in Italy. To this aim, an analysis of non-stationary and non-linear signals was performed on the time series of the Italian databases on respiratory health (ISAYA and GEIRD) including 36,255 individuals overall, S-NAO, and scPDSI indices to search for characteristic periodicities. The ISAYA (Italian Study on Asthma in Young Adults) and GEIRD (Gene Environment Interactions in Respiratory Diseases) studies collected information on respiratory health in general population samples, born between 1925 and 1989 and aged 20-84 years at the time of the interview, from 13 Italian centres. We found that annual asthma total incidence shared the same periodicity throughout the 1957-2006 time interval. Asthma incidence turned out to be correlated with the dynamics of the scPDSI, modulated by the S-NAO, sharing the same averaged 6 year-periodicity. Since climate patterns appear to influence asthma incidence, future studies aimed at elucidating the complex relationships between climate and asthma incidence are warranted.

Identifiants

pubmed: 37923929
doi: 10.1038/s41598-023-46423-2
pii: 10.1038/s41598-023-46423-2
pmc: PMC10624678
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

19047

Informations de copyright

© 2023. The Author(s).

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Auteurs

S Bonomo (S)

CNR Institute of Environmental Geology and Geo-Engineering (CNR-IGAG), Montelibretti, Rome, Italy. sergio.bonomo@cnr.it.

P Marchetti (P)

Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

S Fasola (S)

CNR Institute of Translational Pharmacology (CNR-IFT), Palermo, Italy.

R Vesentini (R)

Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

A Marcon (A)

Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

G Ferrante (G)

Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.

L Antonicelli (L)

Allergy Unit, Ospedali Riuniti, Ancona, Italy.

S Battaglia (S)

Dipartimento PROMISE, University of Palermo, Palermo, Italy.

R Bono (R)

Department of Public Health and Pediatrics, University of Turin, Turin, Italy.

G Squillacioti (G)

Department of Public Health and Pediatrics, University of Turin, Turin, Italy.

N Murgia (N)

Department of Environmental and Prevention Sciences, University of Ferrara, Ferrara, Italy.

P Pirina (P)

Respiratory Unit, Sassari University, Sassari, Italy.

S Villani (S)

Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.

S La Grutta (S)

CNR Institute of Translational Pharmacology (CNR-IFT), Palermo, Italy.

G Verlato (G)

Department of Diagnostics and Public Health, University of Verona, Verona, Italy.

G Viegi (G)

CNR Institute of Clinical Physiology (CNR-IFC), Pisa, Italy.

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