Effects of neutrophil fate on inflammation.
Apoptosis
Autophagy
NETosis
Necroptosis
Pyroptosis
Reverse migration
Journal
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
ISSN: 1420-908X
Titre abrégé: Inflamm Res
Pays: Switzerland
ID NLM: 9508160
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
10
05
2023
accepted:
24
10
2023
revised:
18
09
2023
medline:
20
11
2023
pubmed:
5
11
2023
entrez:
5
11
2023
Statut:
ppublish
Résumé
Neutrophils are important participants in the innate immune response. They rapidly and efficiently identify and clear infectious agents by expressing large numbers of membrane receptors. Upon tissue injury or pathogen invasion, neutrophils are the first immune cells to reach the site of injury and participate in the inflammatory response. A thorough search on PubMed related to neutrophil death or clearance pathways was performed. Inflammatory response and tissue damage can be aggravated when neutrophils are not removed rapidly from the site of injury. Recent studies have shown that neutrophils can be cleared through a variety of pathways, including non-inflammatory and inflammatory death, as well as reverse migration. Non-inflammatory death pathways include apoptosis and autophagy. Inflammatory death pathways include necroptosis, pyroptosis and NETosis. This review highlights the basic properties of neutrophils and the impact of their clearance pathways on the inflammatory response.
Identifiants
pubmed: 37925664
doi: 10.1007/s00011-023-01811-2
pii: 10.1007/s00011-023-01811-2
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2237-2248Subventions
Organisme : Natural Science Foundation of Hunan Province
ID : 2022JJ30521
Organisme : Natural Science Foundation of Hunan Province
ID : 2022JJ40390
Organisme : Project of Hunan Provincial Health Commission
ID : 202217014497
Organisme : Doctoral Research Startup Fund Project of the Second Affiliated Hospital of University of South China
ID : 2021B03
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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