Can underwater endoscopic mucosal resection be an alternative to conventional endoscopic mucosal resection for superficial non-ampullary duodenal epithelial tumors?

duodenal neoplasm endoscopic mucosal resection learning curve superficial non‐ampullary duodenal epithelial tumor underwater endoscopic mucosal resection

Journal

DEN open
ISSN: 2692-4609
Titre abrégé: DEN Open
Pays: Australia
ID NLM: 9918317682706676

Informations de publication

Date de publication:
Apr 2024
Historique:
received: 16 08 2023
revised: 16 10 2023
accepted: 21 10 2023
medline: 6 11 2023
pubmed: 6 11 2023
entrez: 6 11 2023
Statut: epublish

Résumé

Underwater endoscopic mucosal resection (UEMR) is a simpler procedure for superficial non-ampullary duodenal epithelial tumors (SNADET) than conventional endoscopic mucosal resection (cEMR). This study aimed to evaluate whether cEMR can be substituted by UEMR for SNADET in terms of effectiveness, safety, and learning curve. A total of 157 consecutive patients with 203 SNADETs ≤20 mm in diameter, including 107 lesions resected by cEMR and 96 lesions resected by UEMR, between January 2019 and May 2023, were retrospectively recruited. The treatment outcomes were compared between the cEMR and UEMR groups. The risk factors for incomplete resection by UEMR were analyzed using univariate and multivariate analyses. Lesions in the UEMR group were divided chronologically into five periods; thereafter, the en bloc resection rate and procedure time were compared. No significant differences existed between the cEMR and UEMR groups in the mean procedure time (3.9 min vs. 3.6 min, UEMR is safe and effective for SNADET ≤20 mm, regardless of a history of biopsy, and is easy to learn. Thus, UEMR can serve as an alternative to cEMR.

Identifiants

pubmed: 37927952
doi: 10.1002/deo2.312
pii: DEO2312
pmc: PMC10624252
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e312

Informations de copyright

© 2023 The Authors. DEN Open published by John Wiley & Sons Australia, Ltd on behalf of Japan Gastroenterological Endoscopy Society.

Déclaration de conflit d'intérêts

All authors declare no conflicts of interest for this article.

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Auteurs

Hidenori Tanaka (H)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Yuji Urabe (Y)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Hiroki Takemoto (H)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Kazuki Ishibashi (K)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Hirona Konishi (H)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Yuka Matsubara (Y)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Yudai Takehara (Y)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Shin Morimoto (S)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Fumiaki Tanino (F)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Noriko Yamamoto (N)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Hajime Teshima (H)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Junichi Mizuno (J)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Issei Hirata (I)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Hirosato Tamari (H)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Akiyoshi Tsuboi (A)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Ken Yamashita (K)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Takahiro Kotachi (T)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Hidehiko Takigawa (H)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Ryo Yuge (R)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Shiro Oka (S)

Department of Gastroenterology Hiroshima University Hospital Hiroshima Japan.

Classifications MeSH