The volume of the thalamus and hippocampus in a right-handed female episodic migraine group.
episodic migraine
migraine headache characteristics
right-handed female migraineurs
volume of thalamus and hippocampus
white matter lesions
Journal
Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899
Informations de publication
Date de publication:
2023
2023
Historique:
received:
07
07
2023
accepted:
25
09
2023
medline:
6
11
2023
pubmed:
6
11
2023
entrez:
6
11
2023
Statut:
epublish
Résumé
Migraine is a disabling headache with clinical and radiological complications. The aim of this study was to investigate the volume of the thalamus and hippocampus in migraineurs, the role of white matter lesions (WMLs), and the migraine characteristics in volume changes. Brain MRIs of 161 right-handed female episodic migraine patients and 40 right-handed, age-related, healthy women were performed. Left and right thalamus segmentation was performed on the 3D MPRAGE images using the Freesurfer 5.3 image analysis suite. Hippocampal subfield segmentation was based on a novel statistical atlas built primarily upon ultra-high-resolution The left hippocampus had a smaller and the left thalamus had a larger total volume than the right one in both the control ( These findings indicate that WMLs may influence the volume of the right thalamus and hippocampus, while migraine aura and attack frequency may lead to volume changes in different parts of the hippocampi in migraine patients. These data support the necessity of effective migraine management to limit subcortical volume loss in migraineurs.
Sections du résumé
Background/aim
UNASSIGNED
Migraine is a disabling headache with clinical and radiological complications. The aim of this study was to investigate the volume of the thalamus and hippocampus in migraineurs, the role of white matter lesions (WMLs), and the migraine characteristics in volume changes.
Methods
UNASSIGNED
Brain MRIs of 161 right-handed female episodic migraine patients and 40 right-handed, age-related, healthy women were performed. Left and right thalamus segmentation was performed on the 3D MPRAGE images using the Freesurfer 5.3 image analysis suite. Hippocampal subfield segmentation was based on a novel statistical atlas built primarily upon ultra-high-resolution
Results
UNASSIGNED
The left hippocampus had a smaller and the left thalamus had a larger total volume than the right one in both the control (
Conclusion
UNASSIGNED
These findings indicate that WMLs may influence the volume of the right thalamus and hippocampus, while migraine aura and attack frequency may lead to volume changes in different parts of the hippocampi in migraine patients. These data support the necessity of effective migraine management to limit subcortical volume loss in migraineurs.
Identifiants
pubmed: 37928149
doi: 10.3389/fneur.2023.1254628
pmc: PMC10622660
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1254628Informations de copyright
Copyright © 2023 He, Kis-Jakab, Komáromy, Perlaki, Orsi, Bosnyák, Rozgonyi, John, Trauninger, Eklics and Pfund.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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