Co-infection and co-localization of Kaposi sarcoma-associated herpesvirus and Epstein-Barr virus in HIV-associated Kaposi sarcoma: a case report.


Journal

Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359

Informations de publication

Date de publication:
2023
Historique:
received: 01 08 2023
accepted: 04 10 2023
medline: 7 11 2023
pubmed: 6 11 2023
entrez: 6 11 2023
Statut: epublish

Résumé

Kaposi sarcoma (KS), a multifocal vascular neoplasm frequently observed in HIV-positive individuals, primarily affects the skin, mucous membranes, visceral organs, and lymph nodes. KS is associated primarily with Kaposi sarcoma-associated herpesvirus (KSHV) infection. In this case report, we present a rare occurrence of co-infection and co-localization of KSHV and Epstein-Barr virus (EBV) in KS arising from the conjunctiva, which, to our knowledge, has not been reported previously. Immunohistochemistry (IHC), DNA polymerase chain reaction (PCR), and EBV-encoded RNA

Identifiants

pubmed: 37928187
doi: 10.3389/fcimb.2023.1270935
pmc: PMC10623342
doi:

Types de publication

Case Reports Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1270935

Subventions

Organisme : NCI NIH HHS
ID : U54 CA221204
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA036727
Pays : United States

Informations de copyright

Copyright © 2023 Julius, Kang, Siyumbwa, Musumali, Tso, Ngalamika, Kaile, Maate, Moonga, West, Angeletti and Wood.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

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Auteurs

Peter Julius (P)

Department of Pathology and Microbiology, School of Medicine, University of Zambia, Lusaka, Zambia.

Guobin Kang (G)

Department of Interdisciplinary Oncology, Louisiana State University Health Sciences Center - New Orleans, New Orleans, LA, United States.

Stepfanie Siyumbwa (S)

Department of Pathology and Microbiology, School of Medicine, University of Zambia, Lusaka, Zambia.

Jane Musumali (J)

University Teaching Hospitals, Eye Hospital, Ministry of Health, Lusaka, Zambia.

For Yue Tso (FY)

Department of Interdisciplinary Oncology, Louisiana State University Health Sciences Center - New Orleans, New Orleans, LA, United States.

Owen Ngalamika (O)

Department of Pathology and Microbiology, School of Medicine, University of Zambia, Lusaka, Zambia.

Trevor Kaile (T)

Department of Pathology and Microbiology, School of Medicine, University of Zambia, Lusaka, Zambia.

Fred Maate (F)

Department of Pathology and Microbiology, School of Medicine, University of Zambia, Lusaka, Zambia.

Phyllis Moonga (P)

University Teaching Hospitals, Eye Hospital, Ministry of Health, Lusaka, Zambia.

John T West (JT)

Department of Interdisciplinary Oncology, Louisiana State University Health Sciences Center - New Orleans, New Orleans, LA, United States.

Peter Angeletti (P)

Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE, United States.

Charles Wood (C)

Department of Interdisciplinary Oncology, Louisiana State University Health Sciences Center - New Orleans, New Orleans, LA, United States.

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Classifications MeSH