Molecular docking analysis of HSV-1 proteins models with synthetic and plant derived compounds.
HSV
acyclovir
anthraquinone.
anti-HSV drug
Journal
Bioinformation
ISSN: 0973-2063
Titre abrégé: Bioinformation
Pays: Singapore
ID NLM: 101258255
Informations de publication
Date de publication:
2023
2023
Historique:
received:
01
09
2023
revised:
30
09
2023
accepted:
30
09
2023
medline:
6
11
2023
pubmed:
6
11
2023
entrez:
6
11
2023
Statut:
epublish
Résumé
The atomic resolution model of US9, UL20, and gH protein of HSV is known. Hence, the ligand protein interaction of the US9, UL20, and gH protein models were carried out with synthetic drugs like acyclovir, bexarotene, vinorelbine, foscarnet, famciclovir, cidofovir and two plant derived natural drug acacetin and anthraquinone. Based on structure and docking study, it is predicted that protein US20 and gH binds with particular anti-HSV drug i.e. acyclovir, cidofovir, acacetin and famciclovir, acacetin respectively, while interaction of different protein is different with drugs.
Identifiants
pubmed: 37928488
doi: 10.6026/97320630019981
pii: 97320630019981
pmc: PMC10625359
doi:
Types de publication
Journal Article
Langues
eng
Pagination
981-986Informations de copyright
© 2023 Biomedical Informatics.
Déclaration de conflit d'intérêts
Authors declares there is no any conflict of interests
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