Use of a Digital Conversational Agent for the Management of Overactive Bladder.
Journal
Urogynecology (Philadelphia, Pa.)
ISSN: 2771-1897
Titre abrégé: Urogynecology (Phila)
Pays: United States
ID NLM: 9918452588006676
Informations de publication
Date de publication:
06 Nov 2023
06 Nov 2023
Historique:
medline:
6
11
2023
pubmed:
6
11
2023
entrez:
6
11
2023
Statut:
aheadofprint
Résumé
Conservative therapy is effective for the treatment of overactive bladder (OAB) but may be limited by accessibility to care. The objective of this study was to evaluate the efficacy of a digital conversational agent (CeCe) for the treatment of OAB. This was a prospective observational trial utilizing a digital conversational agent developed by Renalis University Hospitals (Cleveland, Ohio) for the treatment of OAB. Patients were given access to CeCe over an 8-week period and were instructed on how to perform bladder training and pelvic floor exercises and taught about bladder health. The primary outcome was a decrease in the International Consultation on Incontinence-Overactive Bladder Quality-of-Life Questionnaire (ICIQ-OAB-QoL) score from week 1 to week 8. Patients also completed the 36-item Short-Form Health Survey and Generalized Anxiety Disorder Questionnaire at the same intervals and voiding diaries at weeks 1, 4, and 8. A power analysis was performed and determined that a total of 30 patients would be needed to demonstrate a significant difference in symptom scores after use of CeCe with 80% power and an α error of 5%. Twenty-nine patients completed all data collection. The ICIQ-OAB-QoL scores were significantly different between weeks 1 and 8 (62 [IQR], 49-75) vs 32 [IQR, 24-43]; P < 0.001). Patients also reported a decrease in frequency pretreatment and posttreatment (7 [IQR, 6-10] vs 5 [IQR, 4-7]; P = -0.04), nocturia (2 [IQR, 1-3] vs 1 [IQR, 1-2]; P = 0.03), and urge urinary incontinence (2 [IQR, 1-5] vs 0 [IQR, 0-3]; P = 0.04). Consumption of alcohol decreased from week 1 to week 8 (24 oz [IQR, 12-36 oz) to 14 oz (IQR, 9-22 oz]; P = 0.02). The use of a digital conversational agent effectively reduced the severity of symptoms and improved quality of life in patients with OAB.
Identifiants
pubmed: 37930265
doi: 10.1097/SPV.0000000000001428
pii: 02273501-990000000-00152
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023 American Urogynecologic Society. All rights reserved.
Déclaration de conflit d'intérêts
D.S. receives research support from Renalis and consulting fee from Caldera. A.H. has ownership stake at Collamedix. S.T.M. receives consulting fee from Boston Scientific and AbbVie. Y.B.C. is chief medical officer of Renalis. N.C. has no conflicts of interest.
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