Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee.


Journal

Seminars in musculoskeletal radiology
ISSN: 1098-898X
Titre abrégé: Semin Musculoskelet Radiol
Pays: United States
ID NLM: 9717520

Informations de publication

Date de publication:
Dec 2023
Historique:
medline: 9 11 2023
pubmed: 8 11 2023
entrez: 7 11 2023
Statut: ppublish

Résumé

Chronic knee pain is a common condition. Causes of knee pain include trauma, inflammation, and degeneration, but in many patients the pathophysiology remains unknown. Recent developments in advanced magnetic resonance imaging (MRI) techniques and molecular imaging facilitate more in-depth research focused on the pathophysiology of chronic musculoskeletal pain and more specifically inflammation. The forthcoming new insights can help develop better targeted treatment, and some imaging techniques may even serve as imaging biomarkers for predicting and assessing treatment response in the future. This review highlights the latest developments in perfusion MRI, diffusion MRI, and molecular imaging with positron emission tomography/MRI and their application in the painful knee. The primary focus is synovial inflammation, also known as synovitis. Bone perfusion and bone metabolism are also addressed.

Identifiants

pubmed: 37935208
doi: 10.1055/s-0043-1775741
pmc: PMC10629992
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

618-631

Informations de copyright

The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

Déclaration de conflit d'intérêts

The University of Wisconsin receives research support from Bracco Diagnostics. E.H.G. Oei has received research support from GE Healthcare. The work of Valentina Mazzoli: was supported by NIH grant K99AG07173502.

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Auteurs

Jacob M Mostert (JM)

Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Niels B J Dur (NBJ)

Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Orthopedics and Sports Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Xiufeng Li (X)

Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota.

Jutta M Ellermann (JM)

Department of Radiology, Center for Magnetic Resonance Research (CMRR), University of Minnesota, Minneapolis, Minnesota.

Robert Hemke (R)

Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.

Laurel Hales (L)

Department of Radiology, Stanford University, Stanford, California.

Valentina Mazzoli (V)

Department of Radiology, Stanford University, Stanford, California.

Feliks Kogan (F)

Department of Radiology, Stanford University, Stanford, California.

James F Griffith (JF)

Department of Imaging and Interventional Radiology Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.

Edwin H G Oei (EHG)

Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Rianne A van der Heijden (RA)

Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Radiology, University of Wisconsin-Madison, Madison, Wisconsin.

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