An artificially-intelligent cornea with tactile sensation enables sensory expansion and interaction.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
07 11 2023
Historique:
received: 25 04 2023
accepted: 03 10 2023
medline: 9 11 2023
pubmed: 8 11 2023
entrez: 7 11 2023
Statut: epublish

Résumé

We demonstrate an artificially-intelligent cornea that can assume the functions of the native human cornea such as protection, tactile perception, and light refraction, and possesses sensory expansion and interactive functions. These functions are realized by an artificial corneal reflex arc that is constructed to implement mechanical and light information coding, information processing, and the regulation of transmitted light. Digitally-aligned, long and continuous zinc tin oxide (ZTO) semiconductor fabric patterns were fabricated as the active channels of the artificial synapse, which are non-toxic, heavy-metal-free, low-cost, and ensure superior comprehensive optical properties (transmittance >99.89%, haze <0.36%). Precisely-tuned crystal-phase structures of the ZTO fibers enabled reconfigurable synaptic plasticity, which is applicable to encrypted communication and associative learning. This work suggests new strategies for the tuning of synaptic plasticity and the design of visual neuroprosthetics, and has important implications for the development of neuromorphic electronics and for visual restoration.

Identifiants

pubmed: 37935671
doi: 10.1038/s41467-023-42240-3
pii: 10.1038/s41467-023-42240-3
pmc: PMC10630301
doi:

Substances chimiques

Zinc Oxide SOI2LOH54Z

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

7181

Informations de copyright

© 2023. The Author(s).

Références

Nat Biomed Eng. 2023 Apr;7(4):511-519
pubmed: 35970931
Ophthalmology. 2002 Mar;109(3):526-9
pubmed: 11874756
Adv Mater. 2021 Dec;33(51):e2105485
pubmed: 34636092
Acta Ophthalmol. 2023 Mar;101(2):222-228
pubmed: 35945658
Lancet. 2012 May 5;379(9827):1749-61
pubmed: 22559901
Prog Neurobiol. 1980;15(1):71-83
pubmed: 7422875
Adv Mater. 2023 Aug;35(33):e2303737
pubmed: 37339620
Nat Commun. 2023 Mar 11;14(1):1344
pubmed: 36906637
Phys Rev Lett. 2002 Mar 4;88(9):095501
pubmed: 11864022
Adv Mater. 2018 Jul 4;:e1801548
pubmed: 29974526
Int J Mol Sci. 2023 Apr 24;24(9):
pubmed: 37175482
Nat Commun. 2022 Nov 10;13(1):6801
pubmed: 36357417
J Am Geriatr Soc. 1979 Jul;27(7):317-8
pubmed: 447996
Sci Adv. 2020 Jun 17;6(25):
pubmed: 32917640
Cornea. 2023 Jul 1;42(7):917-928
pubmed: 37185592
Neurosci Lett. 1997 Jan 24;222(1):33-6
pubmed: 9121716
JAMA Ophthalmol. 2016 Feb;134(2):167-73
pubmed: 26633035
Acta Biomater. 2009 Jan;5(1):438-52
pubmed: 18706878
Am J Ophthalmol. 2011 May;151(5):829-839.e1
pubmed: 21310387
Am J Ophthalmol. 2023 May;249:39-48
pubmed: 36581190
Matter. 2021 Mar 3;4(3):969-985
pubmed: 33398259
Front Med (Lausanne). 2021 Nov 12;8:770780
pubmed: 34869489
Nat Biomed Eng. 2021 Jul;5(7):772-782
pubmed: 33941897
ACS Appl Mater Interfaces. 2014 Aug 27;6(16):14026-36
pubmed: 25090286
Sci Adv. 2021 Mar 31;7(14):
pubmed: 33789904
Pain Res Manag. 2021 Feb 9;2021:6664736
pubmed: 33628353
Phys Rev B Condens Matter. 1996 Oct 15;54(16):11169-11186
pubmed: 9984901
Sci Adv. 2018 Nov 23;4(11):eaat7387
pubmed: 30480091
Front Med (Lausanne). 2022 Sep 29;9:986176
pubmed: 36250075
Ophthalmology. 2014 Nov;121(11):2159-64
pubmed: 25017414
Clin Neurophysiol. 2004 Aug;115(8):1917-20
pubmed: 15261870
Prog Retin Eye Res. 2019 Nov;73:100762
pubmed: 31075321
Annu Rev Vis Sci. 2022 Sep 15;8:1-32
pubmed: 35834821
Am J Ophthalmol. 2019 Sep;205:175-183
pubmed: 30905723
Int J Ophthalmol. 2017 Jul 18;10(7):1154-1162
pubmed: 28730122
Arq Bras Oftalmol. 2022 Sep 23;:
pubmed: 36169436
Surv Ophthalmol. 2022 Jul-Aug;67(4):1175-1199
pubmed: 35081413
J Biomech. 2023 Mar;150:111510
pubmed: 36863199
Cornea. 2018 Sep;37(9):1198-1203
pubmed: 29912039
Nat Commun. 2022 May 17;13(1):2556
pubmed: 35581184
Neuroscience. 2014 Sep 26;277:716-23
pubmed: 25086311
Neurology. 1985 Jun;35(6):797-801
pubmed: 4000481
Curr Biol. 2005 Jul 26;15(14):R554-6
pubmed: 16051164
ACS Nano. 2022 Jul 26;16(7):10632-10646
pubmed: 35802553
Proc Natl Acad Sci U S A. 2022 Jun 7;119(23):e2204852119
pubmed: 35648822
Phys Rev B Condens Matter. 1993 Nov 1;48(17):13115-13118
pubmed: 10007687
Science. 2023 May 19;380(6646):735-742
pubmed: 37200416
Ophthalmology. 2015 Jul;122(7):1504-11
pubmed: 25934510
Acc Chem Res. 2019 Apr 16;52(4):964-974
pubmed: 30896916

Auteurs

Shangda Qu (S)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China.

Lin Sun (L)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China.

Song Zhang (S)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China.

Jiaqi Liu (J)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China.

Yue Li (Y)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China.

Junchi Liu (J)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China.

Wentao Xu (W)

Institute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education, Smart Sensing Interdisciplinary Science Center, Nankai University, Tianjin, 300350, China. wentao@nankai.edu.cn.
Shenzhen Research Institute of Nankai University, Shenzhen, 518000, China. wentao@nankai.edu.cn.

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Classifications MeSH