Influence of psychopathology and metabolic parameters on quality of life in patients with first-episode psychosis before and after initial antipsychotic treatment.
Journal
Schizophrenia (Heidelberg, Germany)
ISSN: 2754-6993
Titre abrégé: Schizophrenia (Heidelb)
Pays: Germany
ID NLM: 9918367987006676
Informations de publication
Date de publication:
07 Nov 2023
07 Nov 2023
Historique:
received:
25
05
2023
accepted:
06
10
2023
medline:
8
11
2023
pubmed:
8
11
2023
entrez:
7
11
2023
Statut:
epublish
Résumé
The impact of psychological and physical health on quality of life (QoL) in patients with early psychosis remain relatively unexplored. We evaluated the predictive value of psychopathological and metabolic parameters on QoL in antipsychotic-naïve patients with first-episode psychosis before and after initial antipsychotic treatment. At baseline, 125 patients underwent assessments of psychopathology, prevalence of metabolic syndrome (MetS), and QoL. After 6 weeks of antipsychotic monotherapy, 89 patients were re-investigated. At baseline, the prevalence of MetS was 19.3% (n = 22). After 6 weeks, body weight (1.3 kg, p < 0.001) and body mass index (0.4 kg/m
Identifiants
pubmed: 37935717
doi: 10.1038/s41537-023-00402-8
pii: 10.1038/s41537-023-00402-8
pmc: PMC10630335
doi:
Types de publication
Journal Article
Langues
eng
Pagination
76Subventions
Organisme : Lundbeckfonden (Lundbeck Foundation)
ID : R377-2021-340
Informations de copyright
© 2023. The Author(s).
Références
Am J Psychiatry. 2010 Jun;167(6):686-93
pubmed: 20360319
JAMA Psychiatry. 2019 Aug 1;76(8):864-867
pubmed: 30942838
Acta Psychiatr Scand. 2021 Dec;144(6):521-523
pubmed: 34587287
JAMA. 2009 Oct 28;302(16):1765-73
pubmed: 19861668
Schizophr Res. 2015 Oct;168(1-2):381-7
pubmed: 26278336
Prev Med Rep. 2017 Jul 19;7:211-215
pubmed: 28794957
Diabet Med. 2006 May;23(5):469-80
pubmed: 16681555
World Health Organ Tech Rep Ser. 2000;894:i-xii, 1-253
pubmed: 11234459
Schizophr Res. 2018 Dec;202:26-36
pubmed: 30005933
Psychol Med. 2003 Aug;33(6):1119-24
pubmed: 12946096
Int J Clin Pract. 2007 Aug;61(8):1356-70
pubmed: 17627711
Arch Gen Psychiatry. 2012 Dec;69(12):1195-204
pubmed: 22868877
J Am Coll Cardiol. 2010 Sep 28;56(14):1113-32
pubmed: 20863953
J Clin Med. 2022 Feb 14;11(4):
pubmed: 35207256
Psychiatr Serv. 2003 Apr;54(4):565-7
pubmed: 12663847
Schizophr Res. 2018 Mar;193:188-196
pubmed: 28663026
Schizophr Res. 2010 Aug;121(1-3):259-65
pubmed: 20655474
Eur Neuropsychopharmacol. 2014 May;24(5):693-709
pubmed: 24275699
Early Interv Psychiatry. 2015 Feb;9(1):53-60
pubmed: 24034336
Soc Psychiatry Psychiatr Epidemiol. 2000 Aug;35(8):348-52
pubmed: 11037303
Acta Psychiatr Scand. 2015 Aug;132(2):97-108
pubmed: 26016380
Psychiatr Serv. 2005 Mar;56(3):292-300
pubmed: 15746503
Schizophr Bull. 1987;13(2):261-76
pubmed: 3616518
Acta Psychiatr Scand. 2021 Dec;144(6):524-536
pubmed: 34458979
Psychol Med. 2021 Oct;51(14):2307-2320
pubmed: 34493353
Soc Sci Med. 1995 Nov;41(10):1403-9
pubmed: 8560308
Psychiatry Investig. 2011 Sep;8(3):201-6
pubmed: 21994506
Psychol Med. 2020 Oct;50(13):2182-2193
pubmed: 31524118
Schizophr Res. 2007 Feb;90(1-3):174-8
pubmed: 17140768
Int J Neuropsychopharmacol. 2013 Jun;16(5):987-95
pubmed: 23253821
Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Jun;5(6):569-579
pubmed: 32008981
Prog Neuropsychopharmacol Biol Psychiatry. 2020 Mar 2;98:109804
pubmed: 31711954
Schizophr Res. 1997 Dec 19;28(2-3):105-9
pubmed: 9468346