Transvenous lead extraction: Efficacy and safety of the procedure in female patients.
Complication
Female sex
Safety outcomes
Sex differences
Transvenous lead extraction
Journal
Heart rhythm O2
ISSN: 2666-5018
Titre abrégé: Heart Rhythm O2
Pays: United States
ID NLM: 101768511
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
medline:
8
11
2023
pubmed:
8
11
2023
entrez:
8
11
2023
Statut:
epublish
Résumé
Existing data on the impact of sex differences on transvenous lead extraction (TLE) outcomes in cardiac device patients are limited. The purpose of this study was to evaluate the safety and efficacy of mechanical TLE in female patients. A retrospective evaluation was performed on 3051 TLE patients (group 1: female; group 2: male) from a single tertiary referral center. All individuals received treatment using single sheath mechanical dilation and various venous approaches as required. Our analysis included 3051 patients (group 1: 750; group 2: 2301), with a total of 5515 leads handled with removal. Female patients were younger, had a higher left ventricular ejection fraction, and lower prevalences of coronary artery disease and diabetes mellitus. Infection was more common in male patients, whereas lead malfunction or abandonment were more frequent in female patients. Radiologic success was lower in female patients (95.8% vs 97.5%; TLE using unpowered simple mechanical sheaths in female patients is safe and effective, but is associated with lower radiologic success and higher complication rates and mortality than in males. This finding underscores the importance of recognizing sex differences in TLE outcomes.
Sections du résumé
Background
UNASSIGNED
Existing data on the impact of sex differences on transvenous lead extraction (TLE) outcomes in cardiac device patients are limited.
Objective
UNASSIGNED
The purpose of this study was to evaluate the safety and efficacy of mechanical TLE in female patients.
Methods
UNASSIGNED
A retrospective evaluation was performed on 3051 TLE patients (group 1: female; group 2: male) from a single tertiary referral center. All individuals received treatment using single sheath mechanical dilation and various venous approaches as required.
Results
UNASSIGNED
Our analysis included 3051 patients (group 1: 750; group 2: 2301), with a total of 5515 leads handled with removal. Female patients were younger, had a higher left ventricular ejection fraction, and lower prevalences of coronary artery disease and diabetes mellitus. Infection was more common in male patients, whereas lead malfunction or abandonment were more frequent in female patients. Radiologic success was lower in female patients (95.8% vs 97.5%;
Conclusion
UNASSIGNED
TLE using unpowered simple mechanical sheaths in female patients is safe and effective, but is associated with lower radiologic success and higher complication rates and mortality than in males. This finding underscores the importance of recognizing sex differences in TLE outcomes.
Identifiants
pubmed: 37936665
doi: 10.1016/j.hroo.2023.09.002
pii: S2666-5018(23)00221-0
pmc: PMC10626182
doi:
Types de publication
Journal Article
Langues
eng
Pagination
625-631Informations de copyright
© 2023 Heart Rhythm Society. Published by Elsevier Inc.
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