CNS therapeutics: Immune cells break the barriers.

Humans Central Nervous System Blood-Brain Barrier Brain Drug Delivery Systems Drug Carriers Central Nervous System Diseases / drug therapy

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
08 Nov 2023
Historique:
medline: 10 11 2023
pubmed: 8 11 2023
entrez: 8 11 2023
Statut: ppublish

Résumé

Peripheral immune cells can be seen as attractive vectors and drug carriers for central nervous system therapeutics because these cells have unique properties that allow them to migrate across the blood-brain barrier, enabling drug delivery to brain regions that are inaccessible to free drugs.

Identifiants

DOI: 10.1126/scitranslmed.adh1150 PMID: 37939159
pubmed: 37939159
doi: 10.1126/scitranslmed.adh1150
doi:

Substances chimiques

Drug Carriers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadh1150

Auteurs

Karine Thai (K)

Neuroimmunology Research Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
ORCID: 0000-0003-4804-0549

Alexandre Prat (A)

Neuroimmunology Research Laboratory, Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Multiple Sclerosis Clinic, Division of Neurology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC H2L 4M1, Canada.
ORCID: 0000-0001-6188-0580

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › CNS therapeutics: Immune cells break the barriers.
questionsmedicales.fr › Système nerveux › Système nerveux central › CNS therapeutics: Immune cells break the barriers.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Barrière hémato-encéphalique › CNS therapeutics: Immune cells break the barriers.
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › CNS therapeutics: Immune cells break the barriers.
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › CNS therapeutics: Immune cells break the barriers.
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › CNS therapeutics: Immune cells break the barriers.
questionsmedicales.fr › Maladies du système nerveux › Maladies du système nerveux central › CNS therapeutics: Immune cells break the barriers.