Aporphine and amide alkaloids from Illigera parviflora.
Alkaloids
Cytotoxicity
Hernandiaceae
Illigera parviflora
Journal
Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R
Informations de publication
Date de publication:
07 Nov 2023
07 Nov 2023
Historique:
received:
17
08
2023
revised:
02
11
2023
accepted:
05
11
2023
pubmed:
9
11
2023
medline:
9
11
2023
entrez:
8
11
2023
Statut:
aheadofprint
Résumé
Three undescribed alkaloids (+)-9-hydroxy-N-acetylnordicentrine (1), illigeparvinine (2), and deca-(2E,4Z)-2,4-dienoic acid 4-hydroxy-2-phenethyl amide (3), along with 19 known analogues (4-22), were isolated from the ethnic medicinal plant Illigera parviflora. Their structures were established using NMR, MS, and other spectroscopic analyses as well as X-ray diffraction. Moderate inhibition of human gastric carcinoma (MGC-803) and breast adenocarcinoma (T-47D) cell lines proliferation was observed for actinodaphnine (4) with IC
Identifiants
pubmed: 37939737
pii: S0367-326X(23)00312-X
doi: 10.1016/j.fitote.2023.105737
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105737Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no conflicts of interest to this work.