Cold atmospheric plasma for surface disinfection: a promising weapon against deleterious meticillin-resistant Staphylococcus aureus biofilms.

Cold atmospheric plasma MRSA Metabolic activity Reduction Resistance Staphylococcus aureus

Journal

The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166

Informations de publication

Date de publication:
07 Nov 2023
Historique:
received: 26 07 2023
revised: 02 10 2023
accepted: 15 10 2023
pubmed: 9 11 2023
medline: 9 11 2023
entrez: 8 11 2023
Statut: aheadofprint

Résumé

Bacteria are becoming increasingly resistant to classical antimicrobial agents, so new approaches need to be explored. To assess the potential of cold atmospheric plasma for the management of meticillin-resistant Staphylococcus aureus (MRSA). The 24, 48, and 72 h resistant and susceptible S. aureus biofilms were exposed to 60, 120, and 180 s treatment with plasma. Increasing the treatment time results in higher cell reduction for both susceptible and resistant strains of S. aureus (P < 0.05). Up to log Cold atmospheric plasma is a good candidate for S. aureus and MRSA biofilm treatment and may therefore be of value in the bacterial resistance crisis.

Sections du résumé

BACKGROUND BACKGROUND
Bacteria are becoming increasingly resistant to classical antimicrobial agents, so new approaches need to be explored.
AIM OBJECTIVE
To assess the potential of cold atmospheric plasma for the management of meticillin-resistant Staphylococcus aureus (MRSA).
METHODS METHODS
The 24, 48, and 72 h resistant and susceptible S. aureus biofilms were exposed to 60, 120, and 180 s treatment with plasma.
FINDINGS RESULTS
Increasing the treatment time results in higher cell reduction for both susceptible and resistant strains of S. aureus (P < 0.05). Up to log
CONCLUSION CONCLUSIONS
Cold atmospheric plasma is a good candidate for S. aureus and MRSA biofilm treatment and may therefore be of value in the bacterial resistance crisis.

Identifiants

pubmed: 37939884
pii: S0195-6701(23)00349-3
doi: 10.1016/j.jhin.2023.10.014
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

64-75

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

M Lunder (M)

University of Ljubljana, Faculty of Health Sciences, Ljubljana, Slovenia.

S Dahle (S)

University of Ljubljana, Biotechnical Faculty, Ljubljana, Slovenia.

R Fink (R)

University of Ljubljana, Faculty of Health Sciences, Ljubljana, Slovenia. Electronic address: rok.fink@zf.uni-lj.si.

Classifications MeSH