Cerebellar Hemangioblastoma with Leptomeningeal Spread and a Fatal Outcome: A Rare Case Report with
epidermal growth factor receptor
fluorescence in situ hybridization
haemangioblastoma
hydrocephalus
immunohistochemistry
mouse double minute 2
Journal
International medical case reports journal
ISSN: 1179-142X
Titre abrégé: Int Med Case Rep J
Pays: New Zealand
ID NLM: 101566269
Informations de publication
Date de publication:
2023
2023
Historique:
received:
23
07
2023
accepted:
21
10
2023
medline:
9
11
2023
pubmed:
9
11
2023
entrez:
9
11
2023
Statut:
epublish
Résumé
Hemangioblastoma (HB) is a Central Nervous System (CNS) tumor with a generally favorable behavior and prognosis, classified as WHO grade 1. Sporadic HB is not related to any inherited disease, and it usually appears in a single location. Sporadic or VHL-related HBs show variable patterns of growth velocity. Cases of growing HB can cause mild symptoms such as headache, but some cases develop serious complications such as accumulation of cerebrospinal fluid in the brain with secondary neurological damage sometimes being irreversible when early treatment is not started. Our case showed some clinical characteristics more frequently observed in VHL-related HB rather than sporadic HB, and the presence of alterations in
Identifiants
pubmed: 37941973
doi: 10.2147/IMCRJ.S428201
pii: 428201
pmc: PMC10629408
doi:
Types de publication
Case Reports
Langues
eng
Pagination
709-714Informations de copyright
© 2023 Chinchilla-Tábora et al.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare for this work.
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