How chromosomal inversions reorient the evolutionary process.
adaptation
balanced polymorphisms
chromosomal rearrangements
inversions
linkage
neutrality
recombination
selection
Journal
Journal of evolutionary biology
ISSN: 1420-9101
Titre abrégé: J Evol Biol
Pays: Switzerland
ID NLM: 8809954
Informations de publication
Date de publication:
08 Nov 2023
08 Nov 2023
Historique:
revised:
13
09
2023
received:
05
05
2023
accepted:
05
10
2023
pubmed:
9
11
2023
medline:
9
11
2023
entrez:
9
11
2023
Statut:
aheadofprint
Résumé
Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach.
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Directorate for Biological Sciences
ID : NSF-DEB 1655701
Organisme : Directorate for Biological Sciences
ID : NSF-OCE 2043905
Organisme : European Commission
ID : ERC AdG 101055327
Organisme : European Society for Evolutionary Biology
Organisme : Fundação para a Ciência e a Tecnologia
ID : 2020.00275.CEECIND
Organisme : Fundação para a Ciência e a Tecnologia
ID : CEECIND/02616/2018
Organisme : Fundação para a Ciência e a Tecnologia
ID : PTDC/BIA- 1232 EVL/1614/2021
Organisme : Leverhulme Trust
ID : RPG-2021-141
Organisme : Norges Forskningsråd
ID : 315287
Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : 310030_204681
Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : 31003A-182262
Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : PZ00P3_185952
Organisme : Vetenskapsrådet
ID : 2021-05243
Organisme : Vetenskapsrådet
ID : 2018-03695
Informations de copyright
© 2023 The Authors. Journal of Evolutionary Biology published by John Wiley & Sons Ltd on behalf of European Society for Evolutionary Biology.
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