Development and Validation of Data-Level Innovation Data-Balancing Machine Learning Models for Predicting Optimal Implantable Collamer Lens Size and Postoperative Vault.

Data-level innovation data-balancing ICL size Machine learning Postoperative vault Prediction

Journal

Ophthalmology and therapy
ISSN: 2193-8245
Titre abrégé: Ophthalmol Ther
Pays: England
ID NLM: 101634502

Informations de publication

Date de publication:
09 Nov 2023
Historique:
received: 13 09 2023
accepted: 20 10 2023
medline: 9 11 2023
pubmed: 9 11 2023
entrez: 9 11 2023
Statut: aheadofprint

Résumé

There are only four sizes of implantable collamer lens (ICL) available for selection, which cannot completely fit all patients as a result of the discontinuity of ICL sizes. Sizing an optimal ICL and predicting postoperative vault are still unresolved problems. This study aimed to develop and validate innovative data-level data-balancing machine learning-based models for predicting ICL size and postoperative vault. The patients were randomly assigned to training and internal validation sets in a 4:1 ratio. Feature selection was performed using analysis of variance (ANOVA) and Kruskal-Wallis feature importance methods. Traditional linear regression model and machine learning-based models were used. The accuracy of models was assessed using the area under the curve (AUC) and confusion matrix. A total of 564 patients (1127 eyes) were eligible for this study, consisting of 808 eyes in the training set, 202 eyes in the internal validation set, and 117 eyes in the external validation set. Compared with the traditional linear regression method, the machine learning model bagging tree showed the best performance for ICL size selection, with an accuracy of 84.5% (95% confidence interval (CI) 83.2-85.8%), and the AUC ranged from 0.88 to 0.99; the prediction accuracy of 12.1 mm and 13.7 mm ICL sizes was improved by 49% and 59%, respectively. The bagging tree model achieved the best accuracy [90.2%, (95% CI 88.9-91.5%)] for predicting the postoperative vault, and the AUC ranged from 0.90 to 0.94. The prediction accuracies of internal and external validation dataset for ICL sizing were 82.2% (95% CI 81.1-83.3%) and 82.1% (95% CI 81.1-83.1%), respectively. The innovative data-level data balancing-based machine learning model can be used to predict ICL size and postoperative vault more accurately, which can assist surgeons in choosing optimal ICL size, thus reducing risks of postoperative complications and secondary surgery.

Identifiants

pubmed: 37943481
doi: 10.1007/s40123-023-00841-7
pii: 10.1007/s40123-023-00841-7
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Capital's Funds for Health Improvement and Research
ID : 2022-1G-4083
Organisme : National Natural Science Foundation of China
ID : 82171092
Organisme : the National Key R&D Program of China
ID : 2021YFC2702100
Organisme : the National Key R&D Program of China
ID : 2020YFC2008200

Informations de copyright

© 2023. The Author(s).

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Auteurs

Heng Zhao (H)

Institute of Medical Technology, Peking University Health Science Center, Beijing, China.
Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Tao Tang (T)

Institute of Medical Technology, Peking University Health Science Center, Beijing, China.
Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Yuchang Lu (Y)

Institute of Medical Technology, Peking University Health Science Center, Beijing, China.
Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Xuewei Li (X)

Institute of Medical Technology, Peking University Health Science Center, Beijing, China.
Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Liyuan Sun (L)

Xuanwu Hospital Capital Medical University, Beijing, China.

Sitong Chen (S)

Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Lu Ma (L)

Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Yan Luo (Y)

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. lawyan@sina.com.

Kai Wang (K)

Institute of Medical Technology, Peking University Health Science Center, Beijing, China. wang_kai@bjmu.edu.cn.
Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China. wang_kai@bjmu.edu.cn.
College of Optometry, Peking University Health Science Center, Beijing, China. wang_kai@bjmu.edu.cn.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China. wang_kai@bjmu.edu.cn.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China. wang_kai@bjmu.edu.cn.

Mingwei Zhao (M)

Institute of Medical Technology, Peking University Health Science Center, Beijing, China.
Department of Ophthalmology and Clinical Centre of Optometry, Peking University People's Hospital, Beijing, China.
College of Optometry, Peking University Health Science Center, Beijing, China.
Eye Disease and Optometry Institute, Peking University People's Hospital, Beijing, China.
Beijing Key Laboratory of the Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China.

Classifications MeSH