Expanding Indications for Surgical Resection in Hepatocellular Carcinoma: What is the Evidence?

Humans Carcinoma, Hepatocellular / surgery Liver Neoplasms / surgery Hepatectomy / methods
Hepatic resection Hepatocellular carcinoma Portal vein tumor thrombosis Surgical resection

Journal

Surgical oncology clinics of North America
ISSN: 1558-5042
Titre abrégé: Surg Oncol Clin N Am
Pays: United States
ID NLM: 9211789

Informations de publication

Date de publication:
Jan 2024
Historique:
medline: 13 11 2023
pubmed: 10 11 2023
entrez: 9 11 2023
Statut: ppublish

Résumé

Hepatic resection is one of the mainstays of curative therapy for hepatocellular carcinoma (HCC). The appropriate selection of resectable candidates requires careful consideration of a multitude of factors including tumor burden (size and number of nodules, presence of vascular involvement, extrahepatic spread), patient factors (performance status, underlying liver function), and availability of other therapies (access to transplantation, interventional procedures, immunotherapies). Historically, hepatic resection for HCC has been reserved for patients with solitary tumors without vascular invasion. However, in well-selected patients HCC tumors multifocal in nature or with vascular invasion should be considered for hepatic resection.

Identifiants

DOI: 10.1016/j.soc.2023.07.004 PMID: 37945148
pubmed: 37945148
pii: S1055-3207(23)00078-9
doi: 10.1016/j.soc.2023.07.004
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

99-109

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Gloria Y Chang (GY)

Department of Surgery, Division of Surgical Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Adam C Yopp (AC)

Department of Surgery, Division of Surgical Oncology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. Electronic address: adam.yopp@utsouthwestern.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Expanding Indications for Surgical Resection...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Carcinome hépatocellulaire › Expanding Indications for Surgical Resection...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Tumeurs du foie › Expanding Indications for Surgical Resection...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie digestive › Hépatectomie › Expanding Indications for Surgical Resection...