The alkynyl-containing compounds from mushrooms and their biological activities.
Alkynyl compounds
Bioactivity
Chemical structures
Mushroom
Journal
Natural products and bioprospecting
ISSN: 2192-2195
Titre abrégé: Nat Prod Bioprospect
Pays: Germany
ID NLM: 101577734
Informations de publication
Date de publication:
10 Nov 2023
10 Nov 2023
Historique:
received:
16
10
2023
accepted:
03
11
2023
medline:
10
11
2023
pubmed:
10
11
2023
entrez:
9
11
2023
Statut:
epublish
Résumé
Mushrooms have been utilized by humans for thousands of years due to their medicinal and nutritional properties. They are a crucial natural source of bioactive secondary metabolites, and recent advancements have led to the isolation of several alkynyl-containing compounds with potential medicinal uses. Despite their relatively low abundance, naturally occurring alkynyl compounds have attracted considerable attention due to their high reactivity. Bioactivity studies have shown that alkynyl compounds exhibit significant biological and pharmacological activities, including antitumor, antibacterial, antifungal, insecticidal, phototoxic, HIV-inhibitory, and immunosuppressive properties. This review systematically compiles 213 alkynyl-containing bioactive compounds isolated from mushrooms since 1947 and summarizes their diverse biological activities, focusing mainly on cytotoxicity and anticancer effects. This review serves as a detailed and comprehensive reference for the chemical structures and bioactivity of alkynyl-containing secondary metabolites from mushrooms. Moreover, it provides theoretical support for the development of chemical constituents containing alkynyl compounds in mushrooms based on academic research and theory.
Identifiants
pubmed: 37946001
doi: 10.1007/s13659-023-00416-w
pii: 10.1007/s13659-023-00416-w
pmc: PMC10636002
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
50Subventions
Organisme : National Natural Science Foundation of China
ID : 32370069
Organisme : National Natural Science Foundation of China
ID : U22A20369
Organisme : Fundamental Research Funds for the Central Universities
ID : 2572023AW40
Organisme : Natural Science Foundation of Heilongjiang Province of China
ID : LH2023C035
Organisme : Key R&D Projects in Shaanxi Province of China
ID : 2023-YBSF-164)
Informations de copyright
© 2023. The Author(s).
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