Aggregation-induced emission (AIE)-active metallacycles with near-infrared emission for photodynamic therapy.

Humans Photochemotherapy / methods Nanoparticles Dermatitis, Phototoxic Photosensitizing Agents / pharmacology Neoplasms / diagnostic imaging

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
23 Nov 2023
Historique:
medline: 27 11 2023
pubmed: 10 11 2023
entrez: 10 11 2023
Statut: epublish

Résumé

Multifunctional metallacycles with solid-state emission are highly important in cancer therapy. Here, an aggregation-induced emission (AIE)-active metallacycle of DTPABT-MC-R is developed with efficient emission in the NIR region in the solid state (PLQYs = 4.92%). DTPABT-MC-R-based nanoparticles also display excellent photo-stability, and impressive photosensitive characteristics (ROS efficiency = 10.74%), finally leading to applications in cellular imaging and photodynamic therapy (PDT).

Identifiants

DOI: 10.1039/d3cc04166b PMID: 37946537
pubmed: 37946537
doi: 10.1039/d3cc04166b
doi:

Substances chimiques

Photosensitizing Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

14021-14024

Auteurs

Qifei Shen (Q)

School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, P. R. China. dongfengdang@xjtu.edu.cn.

Kai Gao (K)

State Key Laboratory for Mechanical Behavior of Materials, Shaanxi International Research Center for Soft Matter, School of Materials Science and Engineering, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.

Zhiqin Zhao (Z)

School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, P. R. China. dongfengdang@xjtu.edu.cn.

Anran Gao (A)

School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, P. R. China. dongfengdang@xjtu.edu.cn.

Yanzi Xu (Y)

School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, P. R. China. dongfengdang@xjtu.edu.cn.

Heng Wang (H)

College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong 518060, China.
ORCID: 0000-0002-6829-7205

Lingjie Meng (L)

School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, P. R. China. dongfengdang@xjtu.edu.cn.
Instrumental Analysis Center, Xi'an Jiao Tong University, Xi'an, 710049, P. R. China.

Mingming Zhang (M)

State Key Laboratory for Mechanical Behavior of Materials, Shaanxi International Research Center for Soft Matter, School of Materials Science and Engineering, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.
ORCID: 0000-0003-3156-7811

Dongfeng Dang (D)

School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, P. R. China. dongfengdang@xjtu.edu.cn.
ORCID: 0000-0003-4697-5447

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Aggregation-induced emission (AIE)-active...
questionsmedicales.fr › Thérapeutique › Photothérapie › Photothérapie dynamique › Aggregation-induced emission (AIE)-active...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Aggregation-induced emission (AIE)-active...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Dermatoses eczémateuses › Eczéma de contact › Dermatite irritative › Dermatite phototoxique › Aggregation-induced emission (AIE)-active...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Radiosensibilisants › Photosensibilisants › Aggregation-induced emission (AIE)-active...
questionsmedicales.fr › Tumeurs › Aggregation-induced emission (AIE)-active...